David A Siegel

6620082, Sep 16, 2003

Oct 21, 2000

09/693442

David S. Siegel - West Palm Beach FL, 33417

A63B 2100

482126, 482124, 482139

The present invention is a device for effectively isolating the shoulder joints and surrounding musculature to provide a strength and conditioning effect while maintaining flexibility about the joint. More specifically, the instantly disclosed apparatus is a butterfly exercise device useful for isolating the pectoral and deltoid muscle groups while rotating the shoulder joint and forearm areas of the user. In its most basic form the device includes first and second members which are constructed and arranged to accept the users forearm and hand. These members are hingedly engaged and are maintained in a first position by variable resistance means. A force, exerted by the users forearms in opposition to the variable resistance means, moves the first and second members to a second position, followed by completion of the repetition by returning to the initial position. While accomplishing the repetition, the user simultaneously rotates both shoulder joints to enhance flexibility while conditioning both the deltoid and pectoral muscle groups.

20020103933, Aug 1, 2002

Jan 29, 2001

09/770298

Ross Garon - New York NY, US
David Siegel - New York NY, US

G06F015/16

709/246000

A system and method are disclosed for quickly and automatically personalizing an Internet-access enabled device based upon a user's pattern of behavior or express preferences on other, possibly incompatible, Internet-access enabled devices. The system and method enable a user to create a personal profile on a first Internet-access enabled device. This profile comprises URLs in the form of bookmarks, a history file, express preferences, or common behaviors derived from a list of URLs. The profile can also include other indicators of preference, such as browser cookies, log files, or the like.

20140274953, Sep 18, 2014

Mar 14, 2013

13/827170

Woo Lee - Ridgewood NJ, US
Jenny Zilberberg - Yardley PA, US
David Samuel Siegel - West Orange NJ, US
Peter Tolias - Westfield NJ, US
Hongjun Wang - Milburn NJ, US
Wenting Zhang - Jersey City NJ, US

G01N 33/50

514 64, 435 723, 435366, 514 94, 514108, 514323

The described invention provides an ex vivo dynamic multiple myeloma (MM) cancer niche contained in a microfluidic device. The dynamic MM cancer niche includes (a) a three-dimensional tissue construct containing a dynamic ex vivo bone marrow (BM) niche, which contains a mineralized bone-like tissue containing viable osteoblasts self-organized into cohesive multiple cell layers and an extracellular matrix secreted by the viable adherent osteoblasts; and a microenvironment dynamically perfused by nutrients and dissolved gas molecules; and (b) human myeloma cells seeded from a biospecimen composition comprising mononuclear cells and the multiple myeloma cells. The human myeloma cells are in contact with osteoblasts of the BM niche, and the viability of the human myeloma cells is maintained by the MM cancer niche.