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Dale G Deutsch

from Stony Brook, NY
Age ~81

Dale Deutsch Phones & Addresses

  • 21 Stony Brook Ave, Stony Brook, NY 11790 (631) 751-2148
  • Port Jefferson, NY
  • East Setauket, NY

Publications

Isbn (Books And Publications)

Analytical Aspects of Drug Testing

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Author

Dale G. Deutsch

ISBN #

0471853097

Us Patents

Fatty Acid Binding Proteins As Drug Targets For Endocannabinoids

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US Patent:
20120165388, Jun 28, 2012
Filed:
Jan 19, 2010
Appl. No.:
13/145058
Inventors:
Dale Deutsch - Stony Brook NY, US
Martin Kaczocha - Dix Hills NY, US
Sherrye Glaser - Dix Hills NY, US
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
A61K 31/7088
A61P 25/00
A61K 31/713
G01N 33/566
US Classification:
514 44 A, 436501
Abstract:
The invention provides a method of modulating the level of an endocannabinoid in a subject in need thereof comprising administering an effective amount of an agent that inhibits the interaction of the endocannabinoid with an intracellular fatty acid binding protein (FABP). The invention also provides a method of identifying an agent for modulating the level of an endo cannabinoid in a subject comprising testing the agent for its ability to modulate binding of the endocannabinoid with an intracellular FABP. The invention also provides a method of identifying an agent for modulating the level of an endocannabinoid in a subject comprising testing the agent for its ability to modulate expression of an intracellular FABP. The invention also provides a method of identifying an agent for treatment of a neurological disorder comprising testing the agent for its ability to modulate the interaction of an endocannabinoid with an intracellular FABP. The invention also relates to modulation of levels of fatty acid amides for treatment or amelioration of diseases or disorders by modulating binding of the fatty acid amides to fatty acid binding proteins. In one embodiment, the fatty acid binding protein is one or more of FABP3, FABP5, and FABP7. In one embodiment, the level of an endocannabinoid is modulated.

Competitive Nucleic Acid Immunoassay For The Detection Of Analytes

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US Patent:
49217887, May 1, 1990
Filed:
Apr 12, 1988
Appl. No.:
7/180543
Inventors:
Dale G. Deutsch - Stony Brook NY
Assignee:
The Research Foundation of State University of New York - Albany NY
International Classification:
C12Q 168
G01N 33535
G01N 33545
US Classification:
435 6
Abstract:
A kit and a method for performing a competitive immunoassay utilize nucleic acid oligonucleotide chains for the detection of analytes, such as drugs, substances of abuse, hormones, poisons, organic compounds, peptides, proteins and the like. The kit includes a hapten-oligonucleotide complex, a complementary oligonculeotide chain for conjugating with the hapten-oligonucleotide complex, an antibody specific for the hapten and a flourescent label such as ethidium bromide having an affinity for nucleic acid duplexes formed from the hapten-oligonucleotide complex and the complementary oligonucleotide chain. A means for detecting the presence of the florescent label such as a U. V. transilluminator, U. V. lightbox and fluorescence spectrophotometer is utilized to detect color intensity and fluorescence of the dye. The method can be performed in solution, or on a solid "dipstick" on which the reagents for the immunoassay have been immobilized.

Alpha- And Gamma-Truxillic Acid Derivatives And Pharmaceutical Compositions Thereof

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US Patent:
20190201365, Jul 4, 2019
Filed:
Feb 15, 2019
Appl. No.:
16/276920
Inventors:
Iwao Ojima - Port Jefferson NY, US
Dale Deutsch - Stony Brook NY, US
Martin Kaczocha - Dix Hills NY, US
William T. Berger - Mastic NY, US
Robert Rizzo - Huntington NY, US
Trent E. Balius - Stony Brook NY, US
Assignee:
The Research Foundation for The State University of New York - Albany NY
International Classification:
A61K 31/216
C07C 69/76
A61K 31/194
G01N 33/68
C07C 67/08
C07C 211/58
C07C 69/757
C07C 69/753
G01N 33/566
C07C 67/48
C07C 235/40
C07C 235/38
C07C 233/58
C07C 233/11
Abstract:
The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, having the structure:

Alpha-Truxillic Acid Derivatives And Pharmaceutical Compositions Thereof

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US Patent:
20190062261, Feb 28, 2019
Filed:
Mar 10, 2017
Appl. No.:
16/080493
Inventors:
- Albany NY, US
Dale Deutsch - Stony Brook NY, US
Martin Kaczocha - Dix Hills NY, US
Kongzhen Hu - Port Jefferson NY, US
Simon Tong - Great Neck NY, US
Matthew Elmes - Stony Brook NY, US
Su Yan - Stony Brook NY, US
Assignee:
The Research Foundation for the State University of New York - Albany NY
International Classification:
C07C 69/753
C07D 249/06
C07D 215/06
C07C 205/55
C07C 69/757
Abstract:
The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, said compound having the structure: Formula (I)

Alpha- And Gamma-Truxillic Acid Derivatives And Pharmaceutical Compositions Thereof

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US Patent:
20170216241, Aug 3, 2017
Filed:
Feb 10, 2017
Appl. No.:
15/429656
Inventors:
Iwao Ojima - Port Jefferson NY, US
Dale Deutsch - Stony Brook NY, US
Martin Kaczocha - Dix Hills NY, US
William T. Berger - Mastic NY, US
Robert Rizzo - Huntington NY, US
Trent E. Balius - Stony Brook NY, US
Assignee:
The Research Foundation for The State University of New York - Albany NY
International Classification:
A61K 31/216
G01N 33/68
A61K 31/194
Abstract:
The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, having the structure:

Alpha- And Gamma-Truxillic Acid Derivatives And Pharmaceutical Compositions Thereof

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US Patent:
20150183715, Jul 2, 2015
Filed:
Jul 19, 2013
Appl. No.:
14/413621
Inventors:
Iwao Ojima - Port Jefferson NY, US
Dale Deutsch - Stony Brook NY, US
Martin Kaczocha - Dix Hills NY, US
William T. Berger - Mastic NY, US
Robert Rizzo - Huntington NY, US
Trent E. Balius - Stony Brook NY, US
Assignee:
The Research Foundation for The State University of New York - Albany NY
International Classification:
C07C 69/757
C07C 67/48
G01N 33/566
C07C 67/08
Abstract:
The present invention provides a compound, and method of inhibiting the activity of a Fatty Acid Binding Protein (FABP) comprising contacting the FABP with a compound, having the structure:
Dale G Deutsch from Stony Brook, NY, age ~81 Get Report