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Craig Wolfangel Phones & Addresses

  • Carmel, IN
  • Sunnyvale, CA
  • Canton, OH
  • 2736 Packard St, Ann Arbor, MI 48108 (734) 973-2854
  • 3123 Woodland Hills Dr, Ann Arbor, MI 48108 (734) 981-5453
  • New Franklin, OH
  • Detroit, MI
  • Canton, MI
  • 3762 Kegler Way, Carmel, IN 46074

Publications

Us Patents

Raf Inhibitor Compounds

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US Patent:
20130252977, Sep 26, 2013
Filed:
Mar 5, 2013
Appl. No.:
13/785575
Inventors:
Michael D. Kaufman - Lawrence KS, US
Phenil J. Patel - Carmel IN, US
Craig D. Wolfangel - Carmel IN, US
Assignee:
DECIPHERA PHARMACEUTICALS, LLC - Lawrence KS
ELI LILLY AND COMPANY - Indianapolis IN
International Classification:
C07D 471/04
US Classification:
51426411, 544279
Abstract:
The present invention provides a pyrido[2,3-d]pyrimidine compound, or a pharmaceutically acceptable salt thereof, that inhibits Raf and, therefore, may be useful in treating cancer.

Tosylate Salt Of N-[3-[(4Ar,7As)-2-Amino-6-(5-Fluoropyrimidin-2-Yl)-4,4A,5,7-Tetrahydropyrrolo[3,4-D][1,3]Thiazin-7A-Yl]-4-Fluoro-Phenyl]-5-Methoxy-Pyrazine-2-Carboxamide

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US Patent:
20170368071, Dec 28, 2017
Filed:
Jan 22, 2016
Appl. No.:
15/535523
Inventors:
- Indianapolis IN, US
Craig Daniel Wolfangel - Carmel IN, US
International Classification:
A61K 31/542
C07D 513/04
Abstract:
The present invention provides a tosylate salt of N-[3-[(4aR,7aS)-2-amino-6-(5-fluoropyrimidin-2-yl)-4,4a,5,7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7a-yl]-4-fluoro-phenyl]-5-methoxy-pyrazine-2-carboxamide.

Aminopyridyloxypyrazole Compounds

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US Patent:
20160096823, Apr 7, 2016
Filed:
Sep 30, 2015
Appl. No.:
14/870033
Inventors:
- Indianapolis IN, US
Sajan JOSEPH - Carmel IN, US
Saravanan PARTHASARATHY - Carmel IN, US
Huaxing PEI - Carmel IN, US
Jason Scott SAWYER - Indianapolis IN, US
Douglas W. BEIGHT - Clinton IN, US
Gaiying ZHAO - Westfield IN, US
David A. COATES - Indianapolis IN, US
Craig D. WOLFANGEL - Carmel IN, US
International Classification:
C07D 401/12
C07D 401/14
C07D 405/14
Abstract:
The present invention relates to novel aminopyridyloxypyrazole compounds that inhibit the activity of transforming growth factor beta receptor 1 (TGFβR1), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, preferably colon cancer, melanoma, hepatocellular carcinoma, renal cancer, glioblastoma, pancreatic cancer, myelodysplastic syndrome, lung cancer, and gastric cancer, and/or fibrosis, preferably liver fibrosis and chronic kidney disease.

3,4-Dihydroisoquinolin-2(1H)-Yl Compounds

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US Patent:
20140357664, Dec 4, 2014
Filed:
May 27, 2014
Appl. No.:
14/287239
Inventors:
- Indianapolis IN, US
David Andrew COATES - Indianapolis IN, US
Junliang HAO - Carmel IN, US
Matthew Robert REINHARD - Indianapolis IN, US
John Mehnert SCHAUS - Indianapolis IN, US
Craig Daniel WOLFANGEL - Carmel IN, US
Assignee:
Eli Lilly and Company - Indianapolis IN
International Classification:
C07D 217/16
US Classification:
514307, 546146
Abstract:
The invention provides certain 3,4-dihydroisoquinolin-2(1H)-yl compounds, particularly compounds of formula I, and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I to treat cognitive impairment associated with Parkinson's disease or schizophrenia.
Craig Daniel Wolfangel from Carmel, IN, age ~50 Get Report