US Patent:
20120328691, Dec 27, 2012
Inventors:
Cliff C. Cheng - Cambridge MA, US
Xiaohua Huang - Malden MA, US
Thierry O. Fischmann - Scotch Plains NJ, US
Jose S. Duca - Cranford NJ, US
Matthew Richards - Somerville MA, US
Hongbo Zeng - Westford MA, US
Binyuan Sun - Chestnut Hill MA, US
Panduranga Adulla Reddy - Walpole MA, US
Tzu T. Wong - Belmont MA, US
Praveen K. Tadikonda - Norwood MA, US
M. Arshad Siddiqui - Newton MA, US
Marc A. Labroli - Moorestown NJ, US
Cory Poker - Bridgewater NJ, US
Timothy J. Guzi - Sudbury MA, US
International Classification:
A61K 31/496
A61K 31/55
C07D 417/12
A61K 31/454
A61K 31/427
A61K 31/541
A61K 31/506
A61K 31/497
C07D 471/10
A61K 31/438
A61K 31/4545
A61K 31/5377
C07D 498/10
A61K 31/5386
A61K 31/551
A61K 33/24
A61K 9/127
A61K 39/395
A61K 31/704
A61K 38/19
A61K 31/7068
A61K 38/50
A61K 38/20
A61K 38/21
A61P 35/00
A61P 35/02
A61N 5/10
C07D 417/14
US Classification:
424450, 544369, 51425402, 544364, 5142531, 540603, 5142171, 546209, 514326, 548200, 514365, 544 587, 5142278, 544295, 51425219, 544357, 51425211, 546 20, 514278, 51425404, 5142102, 546194, 514318, 546193, 544130, 5142368, 51425403, 546 16, 544 71, 544328, 514256, 540575, 514218, 540480, 424649, 4241331, 4241301, 514 34, 424 851, 514 49, 424 946, 424 852, 424 854, 600 1
Abstract:
The present invention relates to novel Anilinopiperazine Derivatives of Formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, cancer, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.