Search

Chetan Bettegowda

from Lutherville Timonium, MD
Age ~49

Chetan Bettegowda Phones & Addresses

  • 6 Dipping Pond Ct, Luthvle Timon, MD 21093 (443) 725-4546
  • Lutherville Timonium, MD
  • Ellicott City, MD
  • 5239 Morning Dove Way, Perry Hall, MD 21128 (443) 725-4546
  • 2201 Rogene Dr, Baltimore, MD 21209 (410) 358-2766
  • 2255 Rogene Dr, Baltimore, MD 21209 (410) 358-2766
  • 2850 Charles St, Baltimore, MD 21218 (410) 662-7449
  • 127 Versailles Cir, Towson, MD 21204 (410) 358-2766
  • Charlotte, NC

Work

Company: JOHNS HOPKINS DEPARTMENT OF NEUROSURGERY Address: 600 N Wolfe St, Baltimore, MD 21287 Phones: (410) 955-2264

Education

School / High School: Johns Hopkins University / School of Medicine 2002

Languages

English

Specialities

Neurosurgery

Professional Records

Medicine Doctors

Chetan Bettegowda Photo 1

Dr. Chetan Bettegowda, Baltimore MD - MD (Doctor of Medicine)

View page
Specialties:
Neurosurgery
Address:
JOHNS HOPKINS DEPARTMENT OF NEUROSURGERY
600 N Wolfe St, Baltimore, MD 21287
(410) 955-2264 (Phone)
Languages:
English
Education:
Medical School
Johns Hopkins University / School of Medicine
Graduated: 2002
Chetan Bettegowda Photo 2

Chetan Bettegowda

View page
Specialties:
Surgery , Neurological
Work:
Johns Hopkins Hospital Pediatric Neurosurgery
600 N Wolfe St STE 556, Baltimore, MD 21287
(410) 955-7851 (phone), (410) 955-7862 (fax)
Education:
Medical School
Johns Hopkins University School of Medicine
Graduated: 2005
Procedures:
Craniotomy
Lumbar Puncture
Spinal Cord Surgery
Spinal Fusion
Spinal Surgery
Conditions:
Intervertebral Disc Degeneration
Intracranial Injury
Languages:
English
Spanish
Description:
Dr. Bettegowda graduated from the Johns Hopkins University School of Medicine in 2005. He works in Baltimore, MD and specializes in Surgery , Neurological. Dr. Bettegowda is affiliated with The Johns Hopkins Hospital.
Chetan Bettegowda Photo 3

Chetan Bettegowda, Baltimore MD

View page
Specialties:
Neurological Surgery
Work:
Johns Hopkins Outpatient Center
601 N Caroline St, Baltimore, MD 21287
Education:
Johns Hopkins University (2005)
Chetan Bettegowda Photo 4

Chetan Bettegowda, Baltimore MD

View page
Specialties:
Neurosurgeon
Address:
600 N Wolfe St, Baltimore, MD 21287

Business Records

Name / Title
Company / Classification
Phones & Addresses
Chetan Bettegowda
Medical Doctor
Johns Hopkins Health Sys Corp
General Hospital
600 N Wolfe St, Baltimore, MD 21287
5300 Alpha Commons Dr, Baltimore, MD 21224
(410) 955-5000

Publications

Us Patents

Imaging Infection With Compounds That Bind To Thymidine Kinase

View page
US Patent:
8273326, Sep 25, 2012
Filed:
Jun 20, 2005
Appl. No.:
11/629607
Inventors:
Martin G. Pomper - Baltimore MD, US
Chetan Bettegowda - Charlotte NC, US
Catherine Foss - Baltimore MD, US
Shibin Zhou - Owings Mills MD, US
Kenneth Kinzler - Baltimore MD, US
Bert Vogelstein - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 51/00
A61K 49/04
US Classification:
424 189, 424 173, 424 91, 424 92, 424 94
Abstract:
The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection.

Combination Bacteriolytic Therapy For The Treatment Of Tumors

View page
US Patent:
8613917, Dec 24, 2013
Filed:
Aug 5, 2011
Appl. No.:
13/198850
Inventors:
Long Dang - Baltimore MD, US
Chetan Bettegowda - Towson MD, US
Kenneth W. Kinzler - Bel Air MD, US
Bert Vogelstein - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 35/00
A01N 63/00
A01N 63/02
C12N 1/20
C12N 3/00
US Classification:
424 9341, 424780, 435242, 4352527, 435842
Abstract:
Current approaches for treating cancer are limited, in part, by the inability of drugs to affect the poorly vascularized regions of tumors. We have found that spores of anaerobic bacteria in combination with agents which interact with microtubules can cause the destruction of both the vascular and avascular compartments of tumors. Two classes of microtubule inhibitors were found to exert markedly different effects. Some agents that inhibited microtubule synthesis, such as vinorelbine, caused rapid, massive hemorrhagic necrosis when used in combination with spores. In contrast, agents that stabilized microtubules, such as the taxane, docetaxel, resulted in slow tumor regressions that killed most neoplastic cells. Remaining cells in the poorly perfused regions of tumors could be eradicated by sporulated bacteria. Mechanistic studies showed that the microtubule destabilizers, but not the microtubule stabilizers, radically reduced blood flow to tumors, thereby enlarging the hypoxic niche in which spores could germinate.

Combination Bacteriolytic Therapy For The Treatment Of Tumors

View page
US Patent:
20070148135, Jun 28, 2007
Filed:
Oct 21, 2004
Appl. No.:
10/568765
Inventors:
Long Dang - Baltimore MD, US
Chetan Bettegowda - Baltimore MD, US
Kenneth Kenzler - Bel Air MD, US
Bert Vogelstein - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 35/74
A61K 31/337
A61K 31/427
US Classification:
424093400, 424623000, 514449000, 514365000
Abstract:
Current approaches for treating cancer are limited, in part, by the inability of drugs to affect the poorly vascularized regions of tumors. We have found that spores of anaerobic bacteria in combination with agents which interact with microtubules can cause the destruction of both the vascular and avascular compartments of tumors. Two classes of microtubule inhibitors were found to exert markedly different effects. Some agents that inhibited microtubule synthesis, such as vinorelbine, caused rapid, massive hemorrhagic necrosis when used in combination with spores. In contrast, agents that stabilized microtubules, such as the taxane docetaxel, resulted in slow tumor regressions that killed most neoplastic cells. Remaining cells in the poorly perfused regions of tumors could be eradicated by sponzlated bacteria. Mechanistic studies showed that the microtubule destabilizers, but not the microtubule stabilizers, radically reduced blood flow to tumors, thereby enlarging the hypoxic niche in which spores could germinate. A single intravenous injection of spores plus selected microtubule-interacting agents was able to cause regressions of several tumors in the absence of excessive toxicity.

Imaging Infection With Compounds That Bind To Thymidine Kinase

View page
US Patent:
20130064767, Mar 14, 2013
Filed:
Aug 28, 2012
Appl. No.:
13/596632
Inventors:
Martin G. Pomper - Baltimore MD, US
Chetan Bettegowda - Charlotte NC, US
Catherine Foss - Baltimore MD, US
Shibin Zhou - Owings Mills MD, US
Kenneth Kinzler - Baltimore MD, US
Bert Vogelstein - Baltimore MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61K 51/04
A61K 49/04
A61K 49/00
US Classification:
424 173, 424 92
Abstract:
The instant invention provides a method for diagnosing an infection in a subject by administering to the subject a compound suitable for imaging which binds to a thymidine kinase present in the infecting organism, and obtaining an image of the subject to determine the presence and location of the compound, wherein a localization of the compound is indicative that the subject has an infection.

Tert Promoter Mutations In Gliomas And A Subset Of Tumors

View page
US Patent:
20200399708, Dec 24, 2020
Filed:
Jul 14, 2020
Appl. No.:
16/928164
Inventors:
- Durham NC, US
- Baltimore MD, US
Nickolas Papadopoulos - Towson MD, US
Kenneth W. Kinzler - Baltimore MD, US
Yuchen Jiao - Columbia MD, US
Chetan Bettegowda - Lutherville MD, US
Darell D. Bigner - Mebane NC, US
Zachary J. Reitman - Durham NC, US
Patrick J. Killela - Durham NC, US
Assignee:
Duke University - Durham NC
The Johns Hopkins University - Baltimore MD
International Classification:
C12Q 1/6886
Abstract:
We surveyed 1,230 tumors of 60 different types and found that tumors could be divided into types with low (

Oligodendroglioma Drive Genes

View page
US Patent:
20180195132, Jul 12, 2018
Filed:
Dec 7, 2017
Appl. No.:
15/834886
Inventors:
- Baltimore MD, US
- Durham NC, US
Chetan Bettegowda - Baltimore MD, US
Nishant Agrawal - Baltimore MD, US
Nickolas Papadopoulos - Towson MD, US
Darell Bigner - Mebane NC, US
Hai Yan - Chapel Hill NC, US
Roger McLendon - Durham NC, US
International Classification:
C12Q 1/6886
Abstract:
Oligodendrogliomas are the second most common malignant brain tumor in adults. These tumors often contain a chromosomal abnormality involving a pericentromeric fusion of chromosomes 1 and 19, resulting in losses of the entire short arm of the former and the long arm of the latter. To identify the molecular genetic basis for this alteration, we performed exomic sequencing of seven anaplastic oligodendrogliomas with chromosome 1p and 19q losses. Among other changes, we found that that CIC (homolog of the gene capicua) on chromosome 19q was somatically mutated in six of the seven cases and that FUBP1 (far upstream element (FUSE) binding protein) on chromosome 1p was somatically mutated in two of the seven cases. Examination of 27 additional oligodendrogliomas revealed 12 and 3 more tumors with mutations of CIC and FUBP1, respectively, 58% of which were predicted to result in truncations of the encoded proteins. These results suggest a critical role for these genes in the biology and pathology of oligodendrocytes.

A Spinal Probe Incorporating An Electromechanical System For Detection And Prevention Of Breaches During Surgery

View page
US Patent:
20170056075, Mar 2, 2017
Filed:
May 6, 2015
Appl. No.:
15/308885
Inventors:
- Baltimore MD, US
Robert Allen - Baltimore MD, US
Chetan Bettegowda - Perry Hall MD, US
Ravi Gaddipati - Colorado Springs CO, US
Luis Herrera - South Gate CA, US
Bradley Isaacs - Merrick NY, US
Sheng-fu Lo - Baltimore MD, US
Eric Xie - Hudson OH, US
Clay Andrews - Westport CT, US
Adarsha Malla - Dublin GA, US
Erica Schwarz - Sahuarita AZ, US
International Classification:
A61B 17/70
A61B 90/00
A61B 17/34
Abstract:
The present invention is directed to an innovative pedicle probe that uses a force-sensing electromechanical system coupled with haptic and visual feedback. The probe of the present invention reduces the rate of pedicle screw breaches during spinal fusion surgery. The probe provides an effective guidance system to aid surgeons in detecting and preventing cortical bone breaches, thereby minimizing risk of intraoperative injury to the patient. Moreover, the probe invention decreases surgeon reliance on intraoperative radiation, reducing harmful exposure to both patients and surgeons.

Use Of The Zmiz1 Marker In Directing Treatment And Predicting Survival In Cancer

View page
US Patent:
20160273050, Sep 22, 2016
Filed:
Mar 16, 2016
Appl. No.:
15/071800
Inventors:
- Baltimore MD, US
Michael Lim - Reisterstown MD, US
Patrick Ha - Sparks Glencoe MD, US
Chetan Bettegowda - Perry Hall MD, US
Taeyoung Hwang - Baltimore MD, US
International Classification:
C12Q 1/68
Abstract:
The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions for treating cancer and predicting patient survival. In one embodiment, a method comprises (a) obtaining a biological sample from the patient; and (b) detecting hypermethylation of ZMIZ1 using primers that specifically bind to CpG island 139 at the alternative promoter of the ZMIZ1 gene.
Chetan Bettegowda from Lutherville Timonium, MD, age ~49 Get Report