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Casim A Sarkar

from Saint Paul, MN
Age ~49
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Also known as:
Casim Ali Sarkar, Casim Saskar
Related to:
Durriya B SarkarSarkar Husain, 83
Connected to:
Akash Sarkar, 25Anindya Sarkar, 50Ankana Sarkar, 33Arghya Sarkar, 37Arpana Sarkar, 48Ashoke K Sarkar, 76Badhan Sarkar, 35Baisali Sarkar, 54Bijay K Sarkar, 43Bipul Sarkar, 52

Casim Sarkar Phones & Addresses

  • Saint Paul, MN
  • 4509 Sansom St, Philadelphia, PA 19139
  • 500 E Grant St APT 1101, Minneapolis, MN 55404
  • 143 Albany St, Cambridge, MA 02139
  • 325 Dentation Dr, Baton Rouge, LA 70808 (225) 769-3630

Work

Position: Craftsman/Blue Collar

Education

Degree: Graduate or professional degree

Resumes

Resumes

Casim Sarkar Photo 1

Casim Sarkar

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Position:
Associate Professor of Biomedical Engineering at University of Minnesota
Location:
Minneapolis, Minnesota
Industry:
Research
Work:
University of Minnesota since Jul 2013
Associate Professor of Biomedical Engineering
University of Pennsylvania Jan 2006 - Jun 2013
Assistant Professor of Bioengineering
University of Zurich Sep 2002 - Dec 2005
NIH Postdoctoral Research Fellow
Massachusetts Institute of Technology Sep 1997 - Aug 2002
Hertz Doctoral Research Fellow
Amgen Jun 2000 - Aug 2000
Intern
Education:
Massachusetts Institute of Technology 1997 - 2002
The University of Texas at Austin 1993 - 1997
Casim Sarkar Photo 2

Casim Sarkar

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Publications

Us Patents

G-Csf Analog Compositions And Methods

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US Patent:
6946548, Sep 20, 2005
Filed:
Sep 10, 2001
Appl. No.:
09/950123
Inventors:
Casim A. Sarkar - Cambridge MA, US
Douglas A. Lauffenburger - Cambridge MA, US
Bruce Tidor - Lexington MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61K038/19
US Classification:
530399, 435 695, 424 851
Abstract:
The present invention relates to granulocyte colony stimulating factor (“G-CSF”) analog polypeptide compositions, related nucleic acids, expression constructs, host cells, and processes for recombinant production of the present G-CSF analogs. The concept detailed herein involves novel mutants of G-CSF, using single substitutions to amino acids, which were rationally chosen to affect the cellular trafficking of G-CSF and/or G-CSFR. In addition, pharmaceutical compositions, and methods of use are provided.

Methods Of Using G-Csf Analog Compositions

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US Patent:
7371370, May 13, 2008
Filed:
Aug 3, 2004
Appl. No.:
10/910087
Inventors:
Casim A. Sarkar - Cambridge MA, US
Douglas A. Lauffenburger - Cambridge MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61K 38/19
US Classification:
424 851, 514 2, 514 8, 514 12
Abstract:
The present invention relates to granulocyte colony stimulating factor (“G-CSF”) polypeptide analog compositions. The concept detailed herein provides methods for screening G-CSF analogs, designed with one or more substitutions to amino acids, and selecting analogs for use as G-CSF replacements or antagonists, and may be generalizable beyond G-CSF analogs as well. In addition, pharmaceutical compositions and methods of use are provided for analogs so selected.

Methods Of Using G-Csf Analog Compositions

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US Patent:
7402304, Jul 22, 2008
Filed:
Jan 31, 2005
Appl. No.:
11/047064
Inventors:
Casim A. Sarkar - Cambridge MA, US
Douglas A. Lauffenburger - Cambridge MA, US
Bruce Tidor - Lexington MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61K 38/19
US Classification:
424 851, 435 695, 530399
Abstract:
The present invention relates to granulocyte colony stimulating factor (“G-CSF”) analog polypeptide compositions, related nucleic acids, expression constructs, host cells, and processes for recombinant production of the present G-CSF analogs. The concept detailed herein involves novel mutants of G-CSF, using single substitutions to amino acids, which were rationally chosen to affect the cellular trafficking of G-CSF and/or G-CSFR. In addition, pharmaceutical compositions, and methods of use are provided.

G-Csf Analog Compositions And Methods

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US Patent:
20020151488, Oct 17, 2002
Filed:
Sep 10, 2001
Appl. No.:
09/950473
Inventors:
Casim Sarkar - Cambridge MA, US
Douglas Lauffenburger - Cambridge MA, US
International Classification:
A61K038/18
C07K014/475
A61K038/20
C07H021/04
C12P021/02
C12N005/06
US Classification:
514/012000, 424/085200, 530/399000, 536/023500, 435/069100, 435/325000, 435/320100
Abstract:
The present invention relates to granulocyte colony stimulating factor (“G-CSF”) polypeptide analog compositions. The concept detailed herein provides methods for screening G-CSF analogs, designed with one or more substitutions to amino acids, and selecting analogs for use as G-CSF replacements or antagonists, and may be generalizable beyond G-CSF analogs as well. In addition, pharmaceutical compositions and methods of use are provided for analogs so selected.

Engineered Bacteria For Oral Delivery Of Glucoregulatory Proteins

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US Patent:
20140242111, Aug 28, 2014
Filed:
Mar 8, 2012
Appl. No.:
14/003596
Inventors:
Casim Ali Sarkar - Minneapolis MN, US
Ting Wun Ng - Philadelphia PA, US
Assignee:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA - Philadelphia PA
International Classification:
A61K 35/74
US Classification:
4242001, 4352523, 424 932
Abstract:
Disclosed is an oral delivery system that overcomes major barriers encountered in the gastrointestinal tract, particularly rapid proteolytic degradation and low intestinal permeability. Provided is a method for oral delivery of an engineered microorganism to a mammal where the microorganism produces a macromolecule having a desired bioavailability outcome.
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Casim A Sarkar from Saint Paul, MN, age ~49 Get Report