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Carl R Illig

from Phoenixville, PA
Age ~68
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Also known as:
Carl Dr Illig, Carl W Illig, Carl W Ill, Carl Ilij
Phone and address:
25 Jonathan Dr, Phoenixville, PA 19460
(610) 933-5060
Related to:
Rebecca IlligSierra Illig, 30Fred FeiockCarol Deininger, 78Lindsay Karich, 42Carol Deininger, 47
Connected to:
Amy Illig, 37Debra A Illig, 60Joshua B Illig, 44Juliet K Illig, 57Lena F Illig, 98Richard A Illig, 63Michael E Illikainen, 84Mary J Illikal, 66Elisa Illing, 42Glen Illing, 65

Carl Illig Phones & Addresses

  • 25 Jonathan Dr, Phoenixville, PA 19460 (610) 933-5060
  • 206 Maple Rd, East Aurora, NY 14052 (585) 652-4314
  • 266 Prospect Ave, East Aurora, NY 14052 (585) 652-4314
  • Rochester, NY
  • Kimberton, PA
  • 25 Jonathan Dr, Phoenixville, PA 19460

Work

Company: W.d kelley foundation Jun 2018 Position: Executive director

Skills

Volunteer Management • Public Speaking • Strategic Planning • Nonprofits • Program Development • Community Outreach • Fundraising • Microsoft Office • Social Media • Marketing • Event Planning • Leadership

Emails

c***[email protected]

Resumes

Resumes

Carl Illig Photo 1

Executive Director

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Work:
W.d Kelley Foundation
Executive Director
W D Kelley Foundation
Associate Executive Director
Skills:
Volunteer Management
Public Speaking
Strategic Planning
Nonprofits
Program Development
Community Outreach
Fundraising
Microsoft Office
Social Media
Marketing
Event Planning
Leadership

Publications

Us Patents

Heteroaryl Amidines, Methylamidines And Guanidines, And Use Thereof As Protease Inhibitors

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US Patent:
6403633, Jun 11, 2002
Filed:
Apr 10, 2001
Appl. No.:
09/828783
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 3138
US Classification:
514438, 514365, 514336, 549 74, 548202, 5462804
Abstract:
The present invention is directed to compounds of Formula I: wherein X is O, S or NR and R -R , Y and Z are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, plasmin and urokinase. Certain of the compounds exhibit direct, selective inhibition of urokinase, or are intermediates useful for forming compounds having such activity.

Amidino Protease Inhibitors

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US Patent:
6414020, Jul 2, 2002
Filed:
May 9, 2001
Appl. No.:
09/851123
Inventors:
Tianbao Lu - Exton PA
Bruce E. Tomczuk - Collegeville PA
Carl R. Illig - Phoenixville PA
Richard M. Soll - Lawrenceville NJ
Assignee:
3- Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 31155
US Classification:
514517, 514518, 514602, 514603, 514604, 514605, 514637, 558 56, 558 58, 564 85, 564 86, 564 92, 564 99, 564244, 564246, 564247
Abstract:
Amidino and benzamidino compounds, including compounds of the formula: wherein R -R , R -R , Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit a number of proteolytic enzymes are described. Also described are methods for preparing the compounds of Formula I.

Methods Of Treating C1S-Mediated Diseases And Conditions And Compositions Thereof

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US Patent:
6492403, Dec 10, 2002
Filed:
Feb 9, 2000
Appl. No.:
09/500783
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Roger F. Bone - Bridgewater NJ
Scott L. Klein - Norristown PA
Troy L. Randle - Lindenwold NJ
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 31427
US Classification:
514365, 514438
Abstract:
Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R , R , R , R , X, Y and Z are defined in the specification.

Compounds And Compositions For Treating C1S-Mediated Diseases And Conditions

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US Patent:
6515002, Feb 4, 2003
Filed:
Sep 26, 2001
Appl. No.:
09/962304
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Roger F. Bone - Bridgewater NJ
Scott L. Klein - Norristown PA
Troy L. Randle - Lindenwold NJ
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
C07D41718
US Classification:
514365, 548204
Abstract:
Disclosed is a method for treating the symptoms of an acute or chronic disorder mediated by the classical pathway of the complement cascade, comprising administering to a mammal in need of such treatment a therapeutically effective amount of a compound of Formula I or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein R , R , R , R , X, Y and Z are defined in the specification.

Aminoguanidines And Alkoxyguanidines As Protease Inhibitors

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US Patent:
6518310, Feb 11, 2003
Filed:
Mar 16, 2001
Appl. No.:
09/809293
Inventors:
Bruce E. Tomczuk - Collegeville PA
Richard M. Soll - Lawrenceville NJ
Tianbao Lu - Exton PA
Cynthia L Fedde - Warrington PA
Carl R Illig - Phoenixville PA
Thomas P. Markotan - Pottstown PA
Thomas P Stagnaro - St. David PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 31255
US Classification:
514613, 5142382, 51425502, 514307, 514311, 514327, 514357, 514426, 514459, 514467, 514517, 514518, 514614, 514617, 514618, 514620, 514626, 514628, 514629, 514630, 514633, 544158, 544384, 546145, 546172, 546221, 546332, 548558, 548561, 549426, 558 48, 558 50, 564123, 564148, 564149, 564150, 564182, 564186, 564217, 564221, 564223, 564163, 564164, 564165, 564167, 564168, 564229
Abstract:
Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR and R -R , R -R , R , R , R , R , R , Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin are described. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, thrombin, plasmin and factor Xa. Certain of the compounds exhibit antithrombotic activity via direct, selective inhibition of thrombin, or are intermediates useful for forming compounds having antithrombotic activity. The invention includes a composition for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation in a mammal, comprising a compound of the invention in a pharmaceutically acceptable carrier. Other uses of compounds of the invention are as anticoagulants either embedded in or physically linked to materials used in the manufacture of devices used in blood collection, blood circulation, and blood storage, such as catheters, blood dialysis machines, blood collection syringes and tubes, blood lines and stents.

Heteroaryl Amidines, Methylamidines And Guanidines, And The Use Thereof As Protease Inhibitors

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US Patent:
6562840, May 13, 2003
Filed:
Feb 26, 2002
Appl. No.:
10/082127
Inventors:
Carl R. Illig - Phoenixville PA
Nalin L. Subasinghe - West Chester PA
James B. Hoffman - Ardmore PA
Kenneth J. Wilson - Exton PA
M. Jonathan Rudolph - Doylestown PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 3147
US Classification:
514312, 514438, 514256
Abstract:
The present invention is directed to compounds of Formula I: wherein X is O, S or NR and R âR , Y and Z are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, plasmin and urokinase. Certain of the compounds exhibit direct, selective inhibition of urokinase, or are intermediates useful for forming compounds having such activity.

Aminoguanidines And Alkoxyguanidines As Protease Inhibitors

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US Patent:
6638931, Oct 28, 2003
Filed:
Nov 28, 2000
Appl. No.:
09/722363
Inventors:
Bruce E. Tomczuk - Collegeville PA
Richard M. Soll - Lawrenceville NJ
Tianbao Lu - Exton PA
Cynthia L. Fedde - Warrington PA
Carl R. Illig - Phoenixville PA
Thomas P. Markotan - Pottstown PA
Thomas P. Stagnaro - St. David PA
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 31255
US Classification:
5142382, 51425502, 514307, 514311, 514327, 514357, 514426, 514459, 514467, 514633, 514517, 514518, 544158, 544384, 546145, 546172, 546221, 546332, 548558, 548561, 549426, 564229
Abstract:
Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR and R -R , R -R , R , R , R , R , R , Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin are described. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, thrombin, plasmin and factor Xa. Certain of the compounds exhibit antithrombotic activity via direct, selective inhibition of thrombin, or are intermediates useful for forming compounds having antithrombotic activity. The invention includes a composition for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation in a mammal, comprising a compound of the invention in a pharmaceutically acceptable carrier. Other uses of compounds of the invention are as anticoagulants either embedded in or physically linked to materials used in the manufacture of devices used in blood collection, blood circulation, and blood storage, such as catheters, blood dialysis machines, blood collection syringes and tubes, blood lines and stents.

Aminoguanidines And Alkoxyguanidines As Protease Inhibitors

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US Patent:
6706765, Mar 16, 2004
Filed:
Feb 6, 2003
Appl. No.:
10/359078
Inventors:
Bruce E. Tomczuk - Collegeville PA
Richard M. Soll - Lawrenceville NJ
Tianbao Lu - Kennet Square PA
Cynthia L. Fedde - Warrington PA
Carl R. Illig - Phoenixville PA
Thomas P. Markotan - Morgantown PA
Thomas P. Stagnaro - Riva MD
Assignee:
3-Dimensional Pharmaceuticals, Inc. - Exton PA
International Classification:
A61K 3118
US Classification:
514605, 558 48, 558 50, 564 95, 564123, 564148, 564149, 564150, 564152, 564163, 564164, 564165, 564167, 564168, 564182, 564186, 564217, 564221, 564223, 564229, 564237, 564238
Abstract:
Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR and R -R , R -R , R , R , R , R , R , Y, Z, n and m are set forth in the specification, as well as hydrates, solvates or pharmaceutically acceptable salts thereof, that inhibit proteolytic enzymes such as thrombin are described. Also described are methods for preparing the compounds of Formula I. The novel compounds of the present invention are potent inhibitors of proteases, especially trypsin-like serine proteases, such as chymotrypsin, trypsin, thrombin, plasmin and factor Xa. Certain of the compounds exhibit antithrombotic activity via direct, selective inhibition of thrombin, or are intermediates useful for forming compounds having antithrombotic activity. The invention includes a composition for inhibiting loss of blood platelets, inhibiting formation of blood platelet aggregates, inhibiting formation of fibrin, inhibiting thrombus formation, and inhibiting embolus formation in a mammal, comprising a compound of the invention in a pharmaceutically acceptable carrier. Other uses of compounds of the invention are as anticoagulants either embedded in or physically linked to materials used in the manufacture of devices used in blood collection, blood circulation, and blood storage, such as catheters, blood dialysis machines, blood collection syringes and tubes, blood lines and stents.
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Carl R Illig from Phoenixville, PA, age ~68 Get Report