Bruno Madore

6353752, Mar 5, 2002

May 14, 1999

09/312027

Bruno Madore - Redwood City CA
Norbert J. Pelc - Los Altos CA

Board of Trustees of the Leland Standford Junior University - Palo Alto CA

A61B 5055

600410, 324307, 324309

In some dynamic applications of MRI, only a part of the field-of-view (FOV) actually undergoes dynamic changes. A class of methods, called reduced-FOV (rFOV) methods, convert the knowledge that some part of the FOV is static or not very dynamic into an increase in temporal resolution for the dynamic part, or into a reduction in the scan time. Although cardiac imaging is an important example of an imaging situation where changes are concentrated into a fraction of the FOV, the rFOV methods developed up to now are not compatible with one of the most common cardiac sequences, the so-called retrospective cine method. The present work is a rFOV method designed to be compatible with cine imaging. An increase by a factor n in temporal resolution or a decrease by n in scan time is obtained in the case where only one n of the FOV is dynamic (the rest being considered static). Results are presented for both Cartesian and spiral imaging.

6714010, Mar 30, 2004

Apr 19, 2002

10/125984

Bruno Madore - Brookline MA

Brigham and Womens Hospital, Inc. - Boston MA

G01V 300

324307

A method for combining UNFOLD with a parallel magnetic resonance imaging (MRI) technique, such as SMASH, SENSE, or SPACE-RIP is provided. When acquiring only one n of the usual amount of k-space data, data is acquired n times faster, but n signals will overlap in the resulting images. By spreading the n signals over all of the available temporal frequency bandwidth, UNFOLD reduces the amount of overlap to n/2. A parallel imaging method with an acceleration n/2 can finish the reconstruction by separating the n/2 overlapped signals. The result is a time series of non-corrupted images that are acquired n times faster than normal.

6903551, Jun 7, 2005

May 1, 2003

10/427400

Bruno Madore - Brookline MA, US

Brigham & Women's Hospital, Inc. - Boston MA

G01V003/00

324309, 324307

A variable density non-Cartesian parallel-imaging method for reconstructing a magnetic resonance (MR) image is provided. In embodiments of the invention, an MR data set is obtained by sampling first and second sampling regions, wherein a first region is sampled with a first sampling density that is higher than a second sampling density of a second region. MR images corrupted by aliasing artifacts are reconstructed from the data obtained with each one of the coil-elements of a coil array. These images can be combined into one, de-aliased image using a modified version of Cartesian SENSE. The modification allows all the available k-space lines to be used in the processing, despite the fact that different k-space regions have different sampling densities (i. e. non-Cartesian sampling). Using all available lines is advantageous in terms of signal-to-noise ratio.

7283859, Oct 16, 2007

Apr 19, 2002

10/125983

Bruno Madore - Brookline MA, US

Brigham and Womens' Hospital, Inc. - Boston MA

A61B 5/05

600410

A method for removing one or more artifacts from a time series of magnetic resonance (MR) images is provided. In one embodiment of the invention, an MR time series of data sets is acquired while changing the k-space that is sampled at each time frame. By using the acquired data, information is produced for a plurality of MR images at different time points, wherein the images contain desired components and one or more artifacts. Changing the k-space locations that are sampled from time frame to time frame makes the artifacts behave in a signature way through time, so that they can be identified as being artifacts and be removed through temporal analysis.

8099148, Jan 17, 2012

Oct 15, 2007

11/974743

Bruno Madore - Brookline MA, US

Brigham and Women's Hospital, Inc. - Boston MA

A61B 5/00

600410, 324307, 324308, 324309

A method for removing one or more artifacts from a time series of magnetic resonance (MR) images is provided. In one embodiment of the invention, an MR time series of data sets is acquired while changing the k-space that is sampled at each time frame. By using the acquired data, information is produced for a plurality of MR images at different time points, wherein the images contain desired components and one or more artifacts. Changing the k-space locations that are sampled from time frame to time frame makes the artifacts behave in a signature way through time, so that they can be identified as being artifacts and be removed through temporal analysis.

8235906, Aug 7, 2012

Dec 30, 2008

12/808590

Bruno Madore - Brookline MA, US

The Brigham And Women's Hospital, Inc. - Boston MA

A61B 8/00

600443, 600437, 382128

A system and method for performing accelerated ultrasound imaging provides significant increases in image acquisition speed using substantially simultaneous transmission of a plurality of ultrasound beams into an object being imaged. The resulting acquired echo signal contributions resulting from the reflection of the simultaneously transmitted beams off different features of the object being imaged are separated by employing a spatial decoding scheme. The spatial decoding scheme characterizes how received signals from features within the object being imaged are measured differently by each of the elements of an ultrasound transducer. The present invention may further include a temporal encoding and decoding scheme, which includes the modulation of a potion of the ultrasound beams transmitted during a portion of ultrasound data acquisition periods, to provide improved separation of the signal components from different features.

8330461, Dec 11, 2012

Dec 10, 2007

12/518266

Bruno Madore - Brookline MA, US

The Brigham and Women's Hospital, Inc. - Boston MA

G01V 3/00

324309, 324307

Embodiments of the present invention relate to accelerated dynamic magnetic resonance imaging (MRI) and, more particularly, to imaging situations where the temporal-encoding strategy is disrupted by time-related events, such as breathing motion.

20130006096, Jan 3, 2013

Dec 10, 2007

12/518253

Bruno Madore - Brookline MA, US

A61B 5/055

600413

Embodiments of the present invention relate to systems and methods for magnetic resonance imaging (MRI) and, more particularly, to cardiac cine MRI in which the cardiac sequences are gated retrospectively. In some embodiments, UNFOLD or related temporally- based imaging (e.g., UNFOLD-SENSE) is combined with retrospective gating to produce, for example, better images of the heart in the late diastolic part of the cardiac cycle.