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Bingren Hu Phones & Addresses

  • Baltimore, MD
  • 6904 Kendall Dr, Miami, FL 33156 (305) 740-6955
  • 7603 145Th St, Miami, FL 33158 (786) 573-3279
  • Palmetto Bay, FL
  • Honolulu, HI
  • 518 W Fayette St #407, Baltimore, MD 21201

Work

Company: University of maryland baltimore Position: Professor

Resumes

Resumes

Bingren Hu Photo 1

Professor

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Location:
Baltimore, MD
Work:
University of Maryland Baltimore
Professor

Business Records

Name / Title
Company / Classification
Phones & Addresses
Bingren Hu
President, Director, Principal
HL BIOTECH, INC
Business Services at Non-Commercial Site
7603 SW 145 Ter, Miami, FL 33158

Publications

Us Patents

Regulation Of Autophagy Pathway Phosphorylation And Uses Thereof

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US Patent:
20100086541, Apr 8, 2010
Filed:
Jul 17, 2009
Appl. No.:
12/505281
Inventors:
Chun WU - San Diego CA, US
John A. Mountzouris - San Diego CA, US
Bingren Hu - Palmetto Bay FL, US
Chunli Liu - Palmetto Bay FL, US
International Classification:
A61K 39/395
C07K 16/00
G01N 33/53
A61P 37/02
US Classification:
4241301, 530330, 435 792
Abstract:
The invention relates to polypeptides and proteins known to function in the autophagy pathway that have novel phosphorylation sites. The invention also relates to antibodies specific to these polypeptides and proteins that are phosphorylated or not phosphorylated at novel phosphorylated sites. The invention also relates to methods of producing these antibodies and use of these antibodies in the treatment of diseases related to autophagocytosis.

Regulation Of Apg8 Phosphorylation And Uses Thereof

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US Patent:
20100092458, Apr 15, 2010
Filed:
Jul 20, 2009
Appl. No.:
12/505782
Inventors:
Chun WU - San Diego CA, US
John A. MOUNTZOURIS - San Diego CA, US
Bingren HU - Palmetto Bay FL, US
Chunli LIU - Palmetto Bay FL, US
International Classification:
A61K 39/395
C07K 5/10
C07K 5/103
C07K 7/06
C07K 7/08
C07K 14/00
C07K 16/00
A61P 43/00
US Classification:
4241301, 530330, 530329, 530328, 530327, 530326, 5303871, 5303879
Abstract:
The invention relates to proteins and peptides of the alpha isoform of light chain 3 (APG8) and antibodies to the APG8 protein, particularly antibodies that specifically bind to the alpha isoform of APG8 when either phosphorylated or not phosphorylated at serine-12 and antibodies that bind to the gamma isoform of APG8 when either phosphorylated or not phosphorylated at serine-9. The invention also relates to methods of producing these antibodies and use of these antibodies in the treatment of diseases related to autophagocytosis.

Regulation Of Autophagy Pathway Phosphorylation And Uses Thereof

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US Patent:
20120258550, Oct 11, 2012
Filed:
Apr 3, 2012
Appl. No.:
13/438770
Inventors:
Chun Wu - San Diego CA, US
John A. Mountzouris - San Diego CA, US
Bingren Hu - Baltimore MD, US
Chunli Liu - Palmetto Bay FL, US
Assignee:
ABGENT - San Diego CA
International Classification:
G01N 33/566
C07K 16/08
C07K 5/117
C07K 5/107
C07K 5/103
C07K 5/113
C07K 7/06
C07K 5/11
US Classification:
436501, 530330, 5303879
Abstract:
The invention relates to polypeptides and proteins known to function in the autophagy pathway that have novel phosphorylation sites. The invention also relates to antibodies specific to these polypeptides and proteins that are phosphorylated or not phosphorylated at novel phosphorylated sites. The invention also relates to methods of producing these antibodies and use of these antibodies in the treatment of diseases related to autophagocytosis.

Methods And Antibodies For Designing And Detecting Mutation-Specific Or Hidden Epitope/Antigena

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US Patent:
20180017549, Jan 18, 2018
Filed:
Aug 15, 2016
Appl. No.:
15/236509
Inventors:
Chunli LIU - Baltimore MD, US
Bingren Hu - Baltimore MD, US
International Classification:
G01N 33/53
C12Q 1/37
C07K 16/18
G01N 33/68
Abstract:
This invention discloses “Artificially Cleaved Epitope (ACE)” methods, antibodies, reagents, immunoassays, and kits for designing and detecting mutation-specific epitopes/antigens. The ACE methods can detect epitopes that are either absent or poorly recognizable or accessible naturally to antibodies, and thus must be specifically and artificially created (free terminals) and/or exposed in samples and sample preparations for antibody detection. The ACE methods comprise ACE antigen design and ACE antigen detection. The ACE methods, antibodies, reagents, immunoassays, and kits are useful in research and discovery, diagnostic, and therapeutic applications. In another aspect, the ACE methods can artificially and specifically expose hidden antigens while reducing the antibody non-specific bindings in all antibody-based applications.

Antibodies And Methods For Detecting And Isolating The Common Conjugation Site-Specific Epitopes/Antigens

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US Patent:
20160245823, Aug 25, 2016
Filed:
Dec 15, 2015
Appl. No.:
14/970376
Inventors:
Chunli LIU - Baltimore MD, US
Bingren Hu - Baltimore MD, US
International Classification:
G01N 33/68
Abstract:
This invention discloses the “Artificially Cleaved Epitope (ACE)” methods, antibodies, reagents, immunoassays, immunoaffinity isolation, and kits for all antibody-based applications of designing, detecting, or isolating the common ACE epitopes/antigens in a sample. The ACE methods can detect or isolate epitopes that are either absent or poorly accessible naturally to antibodies, and thus must be specifically and artificially created (free terminals) and/or exposed in a sample for antibody-based applications. The common ACE structures are those that are the common parts of different macromolecule-to-macromolecule conjugation segments. The ACE methods, antibodies, reagents, immunoassays, and kits are useful in research and discovery, diagnostic, and therapeutic applications.

Methods Of Detecting Conjugation Site-Specific And Hidden Epitope/Antigen

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US Patent:
20150241450, Aug 27, 2015
Filed:
Mar 14, 2015
Appl. No.:
14/658164
Inventors:
Chunli LIU - Baltimore MD, US
Bingren Hu - Baltimore MD, US
International Classification:
G01N 33/68
Abstract:
This invention discloses “Artificially Cleaved Epitope (ACE)” methods, antibodies, reagents, immunoassays, and kits for designing and detecting hidden epitopes/antigens. The ACE methods can detect epitopes that are either absent or poorly accessible naturally to antibodies, and thus must be specifically and artificially created (free terminals) and/or exposed in samples and sample preparations for antibody detection. The ACE structures include, but are not limited to, macromolecule-to-macromolecule conjugation sites, and any types of linear hidden epitopes. The ACE methods comprise ACE antigen design and ACE antigen detection. The ACE methods, antibodies, reagents, immunoassays, and kits are useful in research and discovery, diagnostic, and therapeutic applications. In another aspect, the ACE methods can artificially and specifically expose hidden antigens while reducing the antibody non-specific bindings in all antibody-based applications.
Bingren B Hu from Baltimore, MD, age ~65 Get Report