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Barry L Karger

from Newton, MA
Age ~85
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Also known as:
Barry L Michaelson
Phone and address:
62 Deborah Rd, Newton, MA 02459
(617) 244-4360
Related to:
Madeline DeshazoMolly K Deshazo, 38
Connected to:
Jesse M Karger, 36Kyla Karger, 35Catherine J Karges, 57Mark D Karges, 45Misty Karges, 34Tracey A Karges, 57Linda Kargher, 80Arthur Kargman, 56Howard R Kargman, 71Izabella Kargol, 57

Barry Karger Phones & Addresses

  • 62 Deborah Rd, Newton Center, MA 02459 (617) 244-4360
  • Newton, MA
  • 250 Hammond Pond Pkwy #904, Chestnut Hill, MA 02467 (617) 527-4369
  • Brighton, MA
  • 48 Rosalie Rd, Needham Heights, MA 02494 (781) 444-9224
  • Needham, MA

Work

Company: Northeastern university, barnett institute Position: Professor and director

Industries

Research

Resumes

Resumes

Barry Karger Photo 1

Professor And Director At Northeastern University, Barnett Institute

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Position:
Professor and Director at Northeastern University, Barnett Institute, Director at Northestern Univeristy Barnett Institute and Compton Associates
Location:
Greater Boston Area
Industry:
Research
Work:
Northeastern University, Barnett Institute
Professor and Director
Northestern Univeristy Barnett Institute and Compton Associates since 1963
Director

Business Records

Name / Title
Company / Classification
Phones & Addresses
Barry Karger
Of The Scientific Advisory Board
Forest Protein Inc
Mfg Lab Apparatus
128 Spg St, Lexington, MA 02421
(617) 926-4778
Barry L. Karger
President
HPLC '90, INC
Barnett Institute 360 Huntington Ave, Boston, MA 02115
360 Huntington Ave RM 341, Boston, MA 02115

Publications

Amazon

High Resolution Separation And Analysis Of Biological Macromolecules, Part B: Applications, Volume 271 (Methods In Enzymology)

High Resolution Separation and Analysis of Biological Macromolecules, Part B: Applications, Volume 271 (Methods in Enzymology)

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More th...
Binding

Hardcover

Pages

555

Publisher

Academic Press

ISBN #

0080548180

EAN Code

9780121821722

ISBN #

4

High Resolution Separation And Analysis Of Biological Macromolecules, Part A: Fundamentals, Volume 270 (Methods In Enzymology)

High Resolution Separation and Analysis of Biological Macromolecules, Part A: Fundamentals, Volume 270 (Methods in Enzymology)

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The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More th...
Binding

Hardcover

Pages

622

Publisher

Academic Press

ISBN #

0121821714

EAN Code

9780121821715

ISBN #

2

Studies On Foam Fractionation And Application To Lipoid Materials.

STUDIES ON FOAM FRACTIONATION AND APPLICATION TO LIPOID MATERIALS.

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Author

Barry L. Karger

Binding

Paperback

Publisher

PN

ISBN #

6

Advances In Gas Chromatography 1967. Proceedings Of The Fourth International Symposium Held In New York, N. Y., April 3-6, 1967.

ADVANCES IN GAS CHROMATOGRAPHY 1967. Proceedings of the Fourth International Symposium held in New York, N. Y., April 3-6, 1967.

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Author

A. (Ed); Karger, Barry L.; Wentworth, W. E.; Chen, E.; et.al. Zlatkis

Binding

Hardcover

Publisher

Preston Technical Abstracts Company

ISBN #

5

By Barry L. Karger Introduction To Separation Science (1St First Edition) [Hardcover]

By Barry L. Karger Introduction to Separation Science (1st First Edition) [Hardcover]

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Author

Barry L. Karger

Binding

Hardcover

Publisher

Wiley-Interscience

EAN Code

8601414375207

ISBN #

3

Introduction To Separation Science

Introduction to Separation Science

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used - very good
Author

Barry L. Karger, Lloyd R. Snyder, Csaba Horvath

Binding

Hardcover

Pages

608

Publisher

Wiley-Interscience

ISBN #

0471458600

EAN Code

9780471458609

ISBN #

1

Isbn (Books And Publications)

High Resolution Separation and Analysis of Biological Macromolecules: Fundamentals Methods in Enzymology

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Author

Barry L. Karger

ISBN #

0121821714

High Resolution Separation and Analysis of Biological Macromolecules: Applications

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Author

Barry L. Karger

ISBN #

0121821722

An Introduction to Separation Science

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Author

Barry L. Karger

ISBN #

0471458600

Us Patents

Coated Surface Comprising A Polyvinyl Alcohol (Pva) Based Covalently Bonded Stable Hydrophilic Coating

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US Patent:
6372353, Apr 16, 2002
Filed:
Nov 23, 1998
Appl. No.:
09/197896
Inventors:
Barry L. Karger - Newton MA
Wolfgang Goetzinger - Boston MA
Assignee:
Northeastern University - Boston MA
International Classification:
B32B 904
US Classification:
428447, 428521, 428 357, 428 3691, 4273722, 427387
Abstract:
Coatings suitable for surfaces such as are found in capillary electrophoresis columns and methods for their preparation are disclosed. A coated surface of the invention, preferably an interior surface of a microcapillary, generally includes a surface having an interconnected polymeric coating that includes a functional group attached to the surface and capable of copolymerizing with an organic compound in an organic solvent, and a polymer of the organic compound copolymerized with the functional group. The coating can be covalently or non-covalently attached to the surface and can further include an additional layer of coating material. Preferably, the organic compound is a vinyl ester, and most preferably, vinyl acetate, and the attached polymer forming the exposed surface of the coating is a polyvinyl alcohol, the hydroxyl groups of which can be further derivatized in any desired manner. The coating of the invention creates a new, stable surface, appropriate for CE columns or general surface modification. The coating is stable over a wide pH range and allows highly efficient grafting and/or adsorption of a variety of additional layers, if desired.

Expert System For Analysis Of Dna Sequencing Electropherograms

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US Patent:
6442491, Aug 27, 2002
Filed:
Nov 13, 2000
Appl. No.:
09/711449
Inventors:
Arthur W. Miller - Boston MA
Barry L. Karger - Newton MA
Assignee:
Northeastern University - Boston MA
International Classification:
G01N 3348
US Classification:
702 19, 435 6, 435 911, 4352871, 702 20
Abstract:
A method of analyzing DNA fragments separated electrophoretically is presented. The method includes the use of an expert system that interprets raw or preprocessed signal from the separation. The expert system can be used for real-time base-calling, or applied offline after data acquisition is complete. The expert system is directly applicable to all types of electrophoretic separation used for DNA sequencing, i. e. slab gel, capillary and microchip. Each lane of a multiplex system can consist of 1 to 4 (or even more) different fragment labels. The expert system may also be used with other base-coding schemes, such as those in which more than one base is labeled with a given dye, but the amount of label is different for each base. When the presently disclosed method is applied to DNA sequencing, the resulting interpretation comprises a DNA base sequence with numerical confidences assigned to each base. By use of the presently disclosed method the degree of automation of data processing in high-throughput DNA sequencing is improved, as is the quality of the results.

Polymer Mixtures For High Performance/High Temperature Separation In Capillary Electrophoresis, Especially For Long Read Dna Sequencing

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US Patent:
6476118, Nov 5, 2002
Filed:
Feb 18, 2000
Appl. No.:
09/507496
Inventors:
Barry L. Karger - Newton MA
Lev Kotler - Brighton MA
Wolfgang Goetzinger - Boston MA
Haihong Zhou - Boston MA
Zoran Sosic - Cambridge MA
Assignee:
Northeastern University - Boston MA
International Classification:
C08L 3104
US Classification:
524521, 204451, 204601, 525218
Abstract:
A method of separating a mixture of biopolymers of various lengths using a blend of two linear hydrophilic polymers, particularly polyacrylamides (LPA) or substituted polyacrylamides, one with high weight-average molecular mass and another with low weight-average molecular mass, each present at a low concentration but wherein the concentration of the high weight-average molecular mass LPA is above its entanglement threshold, is disclosed. The matrix is excellent for use in methods of nucleic acid analysis, particularly long read length DNA sequencing.

Multichannel Microscale System For High Throughput Preparative Separation With Comprehensive Collection And Analysis

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US Patent:
6660149, Dec 9, 2003
Filed:
Apr 24, 2000
Appl. No.:
09/530118
Inventors:
Barry L. Karger - Newton MA
Lev Kotler - Brighton MA
Frantisek Foret - Malden MA
Marek Minarik - Winthrop MA
Karel Kleparnik - Brno, CZ
Assignee:
Beckman Coulter, Inc. - Fullerton CA
International Classification:
G01N 2726
US Classification:
204601, 204451, 204452, 204603
Abstract:
A modular multiple lane or capillary electrophoresis (chromatography) system that permits automated parallel separation and comprehensive collection of all fractions from samples in all lanes or columns, with the option of further on-line automated sample fraction analysis, is disclosed. Preferably, fractions are collected in a multi-well fraction collection unit, or plate ( ). The multi-well collection plate ( ) is preferably made of a solvent permeable gel, most preferably a hydrophilic, polymeric gel such as agarose or cross-linked polyacrylamide.

On-Line And Off-Line Deposition Of Liquid Samples For Matrix Assisted Laser Desorption Ionization-Time Of Flight (Maldi-Tof) Mass Spectroscopy

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US Patent:
6674070, Jan 6, 2004
Filed:
Jan 9, 2001
Appl. No.:
09/757079
Inventors:
Barry L. Karger - Newton MA
Frantisek Foret - Malden MA
Jan Preisler - Malden MA
Assignee:
Northeastern University - Boston MA
International Classification:
H01J 4900
US Classification:
250288, 250281, 250282, 250287
Abstract:
A universal interface for continuous on-line liquid sample introduction directly to the time-of-flight mass spectrometer, which can further promote throughput and utility of MALDI-TOF MS, is disclosed. Preferably, the liquid sample includes a matrix, either solid or liquid, for use in matrix-assisted-laser-desorption-ionization, most particularly in a time-of-flight mass spectrometer which can further promote throughput and utility of MALDI-TOF MS. In the method of the invention, the same samples and matrices, both solid and liquid, can be used as in conventional MALDI. In practice of the method of the invention, a solution of sample containing, e. g. , peptide and matrix is infused directly into the source chamber of a mass spectrometer at subatmospheric pressure, deposited on a moving sample holder, such as a rotating quartz wheel, and desorbed by, e. g. , a nitrogen laser. The method of the invention is particularly amenable to multiplexing, the parallel deposition of multiple samples, e. g.

Expert System For Analysis Of Dna Sequencing Electropherograms

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US Patent:
6789020, Sep 7, 2004
Filed:
May 21, 2002
Appl. No.:
10/151795
Inventors:
Arthur W. Miller - Boston MA
Barry L. Karger - Newton MA
Assignee:
Northeastern University - Boston MA
International Classification:
G01N 3348
US Classification:
702 19, 435 6, 435 911, 4352871, 702 20
Abstract:
A method of analyzing DNA fragments separated electrophoretically is presented. The method includes the use of an expert system that interprets raw or preprocessed signal from the separation. The expert system can be used for real-time base-calling, or applied offline after data acquisition is complete. The expert system is directly applicable to all types of electrophoretic separation used for DNA sequencing, i. e. slab gel, capillary and microchip. Each lane of a multiplex system can consist of 1 to 4 (or even more) different fragment labels. The expert system may also be used with other base-coding schemes, such as those in which more than one base is labeled with a given dye, but the amount of label is different for each base. When the presently disclosed method is applied to DNA sequencing, the resulting interpretation comprises a DNA base sequence with numerical confidences assigned to each base. By use of the presently disclosed method the degree of automation of data processing in high-throughput DNA sequencing is improved, as is the quality of the results.

On-Line And Off-Line Deposition Of Liquid Samples For Matrix Assisted Laser Desorption Ionization-Time Of Flight (Maldi-Tof) Mass Spectroscopy

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US Patent:
6825463, Nov 30, 2004
Filed:
Apr 25, 2002
Appl. No.:
10/132064
Inventors:
Barry L. Karger - Newton MA
Frantisek Foret - Malden MA
Jan Preisler - Lelekovice, CZ
Assignee:
Northeastern University - Boston MA
International Classification:
H01J 4900
US Classification:
250288, 250281, 250282, 250287
Abstract:
A universal interface for continuous on-line liquid sample introduction directly to the time-of-flight mass spectrometer, which can further promote throughput and utility of MALDI-TOF MS, is disclosed. Preferably, the liquid sample includes a matrix, either solid or liquid, for use in matrix-assisted-laser-desorption-ionization, most particularly in a time-of-flight mass spectrometer which can further promote throughput and utility of MALDI-TOF MS. In the method of the invention, the same samples and matrices, both solid and liquid, can be used as in conventional MALDI. In practice of the method of the invention, a solution of sample containing, e. g. , peptide and matrix is infused directly into the source chamber of a mass spectrometer at subatmospheric pressure, deposited on a moving sample holder, such as a rotating quartz wheel, and desorbed by, e. g. , a nitrogen laser. The method of the invention is particularly amenable to multiplexing, the parallel deposition of multiple samples, e. g.

Parallel Array Of Independent Thermostats For Column Separations

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US Patent:
6929731, Aug 16, 2005
Filed:
Mar 7, 2001
Appl. No.:
09/979622
Inventors:
Frantisek Foret - Malden MA, US
Barry L. Karger - Newton MA, US
Assignee:
Northeastern University - Boston MA
International Classification:
C02F011/18
US Classification:
204602, 204621, 204601
Abstract:
A thermostat array including an array of two or more capillary columns () or two or more channels in a microfabricated device is disclosed. A heat conductive material () surrounded each individual column or channel in array, each individual column or channel being thermally insulated from every other individual column or channel. One or more independently controlled heating or cooling elements () is positioned adjacent to individual columns or channels within the heat conductive material, each heating or cooling element being connected to a source of heating or cooling, and one or more independently controlled temperature sensing elements () is positioned adjacent to the individual columns or channels within the heat conductive material. Each temperature sensing element is connected to a temperature controller.
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Barry L Karger from Newton, MA, age ~85 Get Report