Resumes
Resumes
Arthur Bertelsen Phones & Addresses
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215 Manor Rd, Ridgewood, NJ 07450 (201) 612-0203
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Teaneck, NJ
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Tenafly, NJ
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New York, NY
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215 Manor Rd, Ridgewood, NJ 07450 (201) 686-6119
Work
Position:
Machine Operators, Assemblers, and Inspectors Occupations
Education
Degree:
High school graduate or higher
Emails
Publications
Us Patents
Genetic Markers Associated With Interferon-Alpha Response
View pageUS Patent:
8535887, Sep 17, 2013
Filed:
May 21, 2010
Appl. No.:
12/785060
Inventors:
Arthur Bertelsen - Ridgewood NJ, US
Jacques Fellay - Durham NC, US
Dongliang Ge - Raleigh NC, US
David B. Goldstein - Durham NC, US
John G. McHutchison - Chapel Hill NC, US
Ping Qiu - Edison NJ, US
Kevin Shianna - Durham NC, US
Jason S. Simon - Westfield NJ, US
Alexander J. Thompson - Durham NJ, US
Thomas Urban - Durham NC, US
Jacques Fellay - Durham NC, US
Dongliang Ge - Raleigh NC, US
David B. Goldstein - Durham NC, US
John G. McHutchison - Chapel Hill NC, US
Ping Qiu - Edison NJ, US
Kevin Shianna - Durham NC, US
Jason S. Simon - Westfield NJ, US
Alexander J. Thompson - Durham NJ, US
Thomas Urban - Durham NC, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
C12Q 1/70
C12Q 1/68
C12Q 1/68
US Classification:
435 611, 435 5, 435 61, 435 612
Abstract:
The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-α). These IFN-α response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-α pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-α, and in methods for selecting the most appropriate therapy for such patients.
Compositions And Methods For The Identification Of Lung Tumor Cells
View pageUS Patent:
20040166527, Aug 26, 2004
Filed:
Apr 1, 2004
Appl. No.:
10/816079
Inventors:
Gary Beaudry - Nutley NJ, US
Stephen Madden - Sudbury MA, US
Arthur Bertelsen - Ridgewood NJ, US
Stephen Madden - Sudbury MA, US
Arthur Bertelsen - Ridgewood NJ, US
International Classification:
C12Q001/68
G01N033/574
C07H021/04
C12N005/08
G01N033/574
C07H021/04
C12N005/08
US Classification:
435/006000, 435/007230, 435/069100, 435/320100, 435/366000, 530/350000, 536/023500
Abstract:
This invention provides compositions and methods for the identification of lung cancer cells. In particular, polynucleotide sequences whose presence is indicative of lung cancer are disclosed. In addition, lung cancer can be identified by detecting the presence of the peptides encoded by these sequences. Antibodies to these peptides are also provided. Also included are gene delivery vehicles and host cells comprising these polynucleotides. Kits containing agents and instructions necessary to perform the screening and detecting methods are also provided.
Vectors And Vector Systems Including Genes Encoding Tumor Suppressor Proteins And Producer Cells Transformed Thereby
View pageUS Patent:
57006571, Dec 23, 1997
Filed:
Dec 13, 1993
Appl. No.:
8/166297
Inventors:
Gary A. Beaudry - Montclair NJ
Arthur H. Bertelsen - Ridgewood NJ
Michael I. Sherman - GlenRidge NJ
Bert Vogelstein - Baltimore MD
Arthur H. Bertelsen - Ridgewood NJ
Michael I. Sherman - GlenRidge NJ
Bert Vogelstein - Baltimore MD
Assignee:
Genzyme Corporation - Framingham MA
International Classification:
C12P 2102
C12P 1934
C12N 510
C12N 701
C12P 1934
C12N 510
C12N 701
US Classification:
435 691
Abstract:
Vectors and vector systems are embodied that include a gene encoding a tumor suppressor protein. In one embodiment, the vector includes a gene encoding a tumor suppressor protein and an inducible promoter controlling the gene encoding a tumor suppressor protein. The tumor suppressor protein may be p53 protein. In another embodiment, there is provided a vector system which comprises a first vector including a gene encoding a tumor suppressor protein, and a second vector containing a nucleic acid sequence encoding an antisense sequence complementary to all or a portion of the gene encoding a tumor suppressor protein. In yet another embodiment, there is provided a vector system which comprises a first vector including a gene encoding a tumor suppressor protein, and a second vector containing a gene which encodes a protein which binds to, and thereby inhibits, the tumor suppressor protein. Such vectors and vector systems enable cells transformed thereby to continue to proliferate such that adequate amounts of infectious viral particles, generated from viral vectors including a gene encoding a tumor suppressor protein, can be harvested for administration to patients.
Expression Systems For Amidating Enzyme
View pageUS Patent:
57892342, Aug 4, 1998
Filed:
Feb 6, 1989
Appl. No.:
7/307366
Inventors:
Arthur H. Bertelsen - Teaneck NJ
Nozer M. Mehta - Rockaway NJ
Gary Agide Beaudry - Montclaire NJ
James P. Gilligan - Union NJ
Barry N. Jones - Wayne PA
Nozer M. Mehta - Rockaway NJ
Gary Agide Beaudry - Montclaire NJ
James P. Gilligan - Union NJ
Barry N. Jones - Wayne PA
Assignee:
Unigene Laboratories, Inc. - Fairfield NJ
International Classification:
C12N 510
C12N 1563
C12N 121
C07H 2104
C12N 1563
C12N 121
C07H 2104
US Classification:
4352402
Abstract:
Alpha-amidating enzyme is produced by recombinant DNA techniques recoverable in high yields and at high purity. Both eukaryotic and prokaryotic expression vectors are provided having a transcriptional promoter followed downstream by a DNA sequence which encodes amidating enzyme. The vector selected is one capable of directing the expression of polypeptides in the host selected, and preferred hosts are transected with the described vectors.
Inhibition Of Interferon-.Gamma. With Oligonucleotides
View pageUS Patent:
55999174, Feb 4, 1997
Filed:
Mar 17, 1994
Appl. No.:
8/210222
Inventors:
George R. Coppola - Hartsdale NY
Bruce A. Beutel - Suffern NY
Arthur H. Bertelsen - Ridgewood NJ
Bruce A. Beutel - Suffern NY
Arthur H. Bertelsen - Ridgewood NJ
Assignee:
PharmaGenics, Inc. - Allendale NJ
International Classification:
C12N 1500
C12N 500
A61K 4800
C12N 500
A61K 4800
US Classification:
536 221
Abstract:
Oligonucleotides and analogs thereof that bind to and preferably modulate the activity of interferon-. gamma. , and methods for their use, including therapeutic and diagnostic methods are disclosed.