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Anton Mccaffrey Phones & Addresses

  • San Diego, CA
  • Idyllwild, CA
  • Spring Valley, CA
  • El Cajon, CA
  • Iowa City, IA
  • Boulder, CO
  • Pacifica, CA

Work

Company: Trilink biotechnologies 2011 Position: Head of cell biology

Education

Degree: PhD School / High School: University of Colorado at Boulder 1992 to 1999 Specialities: Biochemistry

Skills

Rnai • Dna • Cell Biology • Molecular Biology • Molecular Cloning • Pcr • Rna • Intellectual Property • Biotechnology • Biochemistry • Project Management • Western Blotting

Languages

English

Interests

Therapeutics • Messenger Rna • Rna • Drug Development • Nucleic Acids • Rna Interference

Industries

Biotechnology

Resumes

Resumes

Anton Mccaffrey Photo 1

Senior Director Of Emerging Science And Innovation

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Location:
4944 Cass St, San Diego, CA 92109
Industry:
Biotechnology
Work:
TriLink BioTechnologies since 2011
Head of Cell Biology

University of Iowa Sep 2004 - Feb 2011
Assistant Professor

Stanford University School of Medicine 1998 - 2004
Postdoctoral Fellow
Education:
University of Colorado at Boulder 1992 - 1999
PhD, Biochemistry
Skills:
Rnai
Dna
Cell Biology
Molecular Biology
Molecular Cloning
Pcr
Rna
Intellectual Property
Biotechnology
Biochemistry
Project Management
Western Blotting
Interests:
Therapeutics
Messenger Rna
Rna
Drug Development
Nucleic Acids
Rna Interference
Languages:
English

Publications

Us Patents

Zinc-Finger Nuclease And Rna Interference Mediated Inactivation Of Viral Genomes

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US Patent:
20120297495, Nov 22, 2012
Filed:
Jun 12, 2012
Appl. No.:
13/494896
Inventors:
Anton P. McCaffrey - San Diego CA, US
Thomas J. Cradick - Atlanta GA, US
Assignee:
UNIVERSITY OF IOWA RESEARCH FOUNDATION - Iowa City IA
International Classification:
A61K 38/46
C12N 15/62
C12N 15/113
A61P 31/20
A01K 67/027
A61K 31/711
A61P 31/12
C12N 9/16
A61K 31/7088
US Classification:
800 18, 435196, 536 232, 536 245, 514 44 R, 424 946
Abstract:
Embodiments of the present invention provide methods for targeted inactivation of viral genomes. In one embodiment, zinc-finger proteins in which DNA binding sites are altered such that they recognize and bind different, desired DNA sequences contained in hepatitis B virus (HBV) and that include nuclease domains are used for inactivation. Other embodiments for targeted inactivation of viral genomes use small nucleic acid molecules, such as short micro-RNA molecules or short hairpin RNA molecules capable of mediating RNA interference (RNAi) against the hepatitis B virus.

Compositions And Methods For Synthesizing 5'-Capped Rnas

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US Patent:
20220289786, Sep 15, 2022
Filed:
May 26, 2022
Appl. No.:
17/804192
Inventors:
- San Diego CA, US
Alexandre LEBEDEV - San Diego CA, US
Anton P. MCCAFFREY - San Diego CA, US
Dongwon SHIN - San Diego CA, US
Assignee:
TriLink Biotechnologies, LLC - San Diego CA
International Classification:
C07H 21/02
A61K 31/7115
A61K 31/712
A61K 31/711
A23L 33/13
C12N 15/11
C12P 19/34
Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form Gppp[N][N]wherein G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.

Compositions And Methods For Synthesizing 5'-Capped Rnas

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US Patent:
20210371452, Dec 2, 2021
Filed:
Aug 2, 2021
Appl. No.:
17/392170
Inventors:
- San Diego CA, US
Alexandre LEBEDEV - San Diego CA, US
Anton P. MCCAFFREY - San Diego CA, US
Dongwon SHIN - San Diego CA, US
Assignee:
TriLink Biotechnologies, LLC - San Diego CA
International Classification:
C07H 21/02
A61K 31/711
A61K 31/712
C12N 15/11
A23L 33/13
C12P 19/34
A61K 31/7115
Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form Gppp[N][N]wherein G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.

Compositions And Methods For Synthesizing 5'-Capped Rnas

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US Patent:
20210261597, Aug 26, 2021
Filed:
Nov 6, 2020
Appl. No.:
17/091422
Inventors:
- San Diego CA, US
Alexandre LEBEDEV - San Diego CA, US
Anton P. MCCAFFREY - San Diego CA, US
Dongwon SHIN - San Diego CA, US
Assignee:
TriLink Biotechnologies, LLC - San Diego CA
International Classification:
C07H 21/02
A61K 31/7115
A61K 31/712
A61K 31/711
A23L 33/13
C12N 15/11
C12P 19/34
Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form Gppp[N][N]wherein G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.

Compositions And Methods For Synthesizing 5'-Capped Rnas

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US Patent:
20190270766, Sep 5, 2019
Filed:
Apr 1, 2019
Appl. No.:
16/371317
Inventors:
- San Diego CA, US
Alexandre LEBEDEV - San Diego CA, US
Anton P. MCCAFFREY - San Diego CA, US
Dongwon SHIN - San Diego CA, US
Assignee:
TRILINK BIOTECHNOLOGIES, INC. - San Diego CA
International Classification:
C07H 21/02
A61K 31/711
C12P 19/34
C12N 15/11
A23L 33/13
A61K 31/712
A61K 31/7115
Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form Gppp[N][N]wherein G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.

Compositions And Methods For Synthesizing 5'-Capped Rnas

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US Patent:
20190144490, May 16, 2019
Filed:
Dec 26, 2018
Appl. No.:
16/232435
Inventors:
- San Diego CA, US
Alexandre Lebedev - San Diego CA, US
Anton P. McCaffrey - San Diego CA, US
Dongwon Shin - San Diego CA, US
Assignee:
TRILINK BIOTECHNOLOGIES, INC. - San Diego CA
International Classification:
C07H 21/02
A61K 31/711
C12P 19/34
C12N 15/11
A61K 31/7115
A23L 33/13
A61K 31/712
Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form Gppp[N][N]wherein G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.

Compositions And Methods For Synthesizing 5'-Capped Rnas

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US Patent:
20180273576, Sep 27, 2018
Filed:
Sep 20, 2016
Appl. No.:
15/761957
Inventors:
- San Diego CA, US
Alexandre LEBEDEV - San Diego CA, US
Anton P. MCCAFFREY - San Diego CA, US
Dongwon SHIN - San Diego CA, US
Assignee:
TRILINK BIOTECHNOLOGIES, INC. - San Diego CA
International Classification:
C07H 21/02
C12P 19/34
C12N 15/11
Abstract:
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form Gppp[N][N]wherein G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.
Anton Patrick Mccaffrey from San Diego, CA, age ~58 Get Report