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Andrew Z Sledziewski

from Shoreline, WA
Age ~72
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Also known as:
Andrew Dr Sledziewski, Andrzej Z Sledziewski, Andrezej Z Sledziewska, Andrezej Sledziewska Dr
Related to:
Karen M Owens, 79Janene L Russell, 51Velma Russell, 70Shirley J RussellElaine Hackworth, 29Harold Russell
Connected to:
Anthony L Sledzieski, 68Brian J Sledziona, 45Bonnie S Slee, 65Christopher Slee, 63Julian A Slee, 59Russell D Slee, 62Steve F Slee, 72John Sleeba, 50Patricia L Sleebos, 63Peter J Sleegers, 86

Andrew Sledziewski Phones & Addresses

  • Shoreline, WA

Work

Company: Epigenomics ag 1998 to 2011 Position: Vice president research

Skills

Biotechnology • Life Sciences • Start Ups • Genomics • Molecular Biology • Lifesciences • Oncology • Strategic Planning • Medical Devices • Pharmaceutical Industry • Product Development • Business Strategy • Biopharmaceuticals • Entrepreneurship

Industries

Biotechnology

Resumes

Resumes

Andrew Sledziewski Photo 1

Chief Executive Officer

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Location:
Seattle, WA
Industry:
Biotechnology
Work:
Epigenomics Ag 1998 - 2011
Vice President Research
Metheor Therapeutics Corp 1998 - 2011
Chief Executive Officer
Skills:
Biotechnology
Life Sciences
Start Ups
Genomics
Molecular Biology
Lifesciences
Oncology
Strategic Planning
Medical Devices
Pharmaceutical Industry
Product Development
Business Strategy
Biopharmaceuticals
Entrepreneurship

Business Records

Name / Title
Company / Classification
Phones & Addresses
Andrew Sledziewski
Chief Executive Officer
METHEOR THERAPEUTICS CORPORATION
Biotechnology · Drug Discovery Research
17736 15 Ave NW, Shoreline, WA 98177

Publications

Us Patents

Methods And Nucleic Acids For Analysis Of Cellular Proliferative Disorders

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US Patent:
7951563, May 31, 2011
Filed:
Apr 17, 2006
Appl. No.:
11/911617
Inventors:
Juergen Distler - Berlin, DE
Thomas Hildmann - Berlin, DE
Ralf Lesche - Berlin, DE
Fabian Model - Berlin, DE
Matthias Schuster - Berlin, DE
Andrew Z. Sledziewski - Shoreline WA, US
Reimo Tetzner - Berlin, DE
Xiaoling Song - Woodinville WA, US
Assignee:
Epigenomics AG - Berlin
International Classification:
C12P 19/34
C12Q 1/68
US Classification:
435 912, 435 6
Abstract:
Aspects of the invention provide methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among liver cell proliferative disorders or for detecting, or for detecting and distinguishing between or among colorectal cell proliferative disorders. Particular aspects disclose and provide genomic sequences the methylation patterns of which have substantial utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.

Method For Methylation Analysis

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US Patent:
8623599, Jan 7, 2014
Filed:
Jun 6, 2008
Appl. No.:
12/451943
Inventors:
Theo Devos - Seattle WA, US
Andrew Sledziewski - Shoreline WA, US
Fabian Model - Berlin, DE
Michael Krouse - Seattle WA, US
Jesse Ho - Seattle WA, US
Matthias Schuster - Singapore, SG
Juergen Distler - Berlin, DE
Reimo Tetzner - Berlin, DE
Assignee:
Epigenomics AG - Berlin
International Classification:
C12Q 1/68
US Classification:
435 61, 435 611
Abstract:
Aspects of the invention relate to composition and methods for the providing of DNA for methylation analysis that is in particular suitable to be applied in reference laboratories. Further 5 aspects of the invention relate to composition and methods for the highly specific and sensitive methylation analysis of the Septin 9 gene also in particular suitable to be applied in reference laboratories.

Method For The Analysis Of Cytosine Methylation Patterns

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US Patent:
20030215842, Nov 20, 2003
Filed:
Jan 30, 2003
Appl. No.:
10/356792
Inventors:
Andrew Sledziewski - Shoreline WA, US
Richard Schweikhardt - Seattle WA, US
Assignee:
Epigenomics AG
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The present invention provides a novel method for the systematic identification of differentially methylated CpG dinucleotides positions within genomic DNA sequences for use as reliable diagnostic, prognostic and/or staging markers. Particular embodiments comprise genome-wide identification of differentially methylated CpG dinucleotide sequences, further identification of neighboring differentially methylated CpG dinucleotide sequences, and confirmation of the diagnostic utility of selected differentially methylated CpG dinucleotide among a larger set of diseased and normal biological samples. The method, and kits for implementation thereof, are useful in applied assays for the diagnosis, prognosis and/or staging of conditions characterized by differential methylation.

Methods And Nucleic Acids For The Analysis Of Cpg Dinucleotide Methylation Status Associated With The Development Of Peripheral Zone Prostate Cancer

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US Patent:
20040146868, Jul 29, 2004
Filed:
Jan 24, 2003
Appl. No.:
10/350763
Inventors:
Susan Cottrell - Seattle WA, US
Andrew Sledziewski - Shoreline WA, US
Assignee:
Epigenomics AG - Berlin
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The present invention provides for molecular GSTP1 markers that have novel utility for the analysis of methylation patterns within the promoter region and exons 1 and 2 of the GSTP1 gene, and are further useful in methods to effectively distinguish among benign hyperplasia of the prostate and different grades of prostate cancer. Additionally, the subject molecular GSTP1 markers have novel utility for the precise localization of the zone of origin to provide sensitive, accurate and non-invasive methods for the diagnosis and/or prognosis of prostate cell proliferative disorders. The present invention has novel utility for the detection and differentiation of a cell proliferative disorder of the peripheral zone of the prostate.

Methods And Nucleic Acids For The Analysis Of Colorectal Cell Proliferative Disorders

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US Patent:
20040265833, Dec 30, 2004
Filed:
Jun 23, 2003
Appl. No.:
10/602494
Inventors:
Andrew Sledziewski - Shoreline WA, US
Jeff Thomas - Bellevue WA, US
Robert Day - Seattle WA, US
Lori Tonnes-Priddy - Everett WA, US
Karen Cardon - Renton WA, US
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The present invention provides, inter alia, novel diagnostic and prognostic methods for detecting, or for detecting and differentiating between or among colorectal cell proliferative disorders. Preferably, said colorectal cell proliferative disorders are selected from the group consisting of colorectal carcinoma, colon adenomas, and colon polyps. The inventive methods are based on analysis of differential CpG dinucleotide methylation of genomic DNA between or among normal and disease states. Additional embodiments provide nucleic acids and oligomers (including oligonucleotides and peptide nucleic acid (PNA)-oligomers), nucleic acid arrays and kits useful for practicing said methods, and in otherwise detecting, or detecting and differentiating between or among colorectal cell proliferative disorders.

Methods And Nucleic Acids For The Analyses Of Cellular Proliferative Disorders

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US Patent:
20060286576, Dec 21, 2006
Filed:
Apr 17, 2006
Appl. No.:
11/405322
Inventors:
Andrew Sledziewski - Shoreline WA, US
Ralf Lesche - Berlin, DE
Matthias Schuster - Berlin, DE
Juergen Distler - Berlin, DE
Reimo Tetzner - Berlin, DE
Thomas Hildmann - Berlin, DE
Fabian Model - Seattle WA, US
Xiaoling Song - Woodinville WA, US
Assignee:
Epigenomics AG - Berlin
International Classification:
C12Q 1/68
C07H 21/04
C12P 19/34
US Classification:
435006000, 435091200, 536024300
Abstract:
The invention provides methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among liver cell proliferative disorders or for detecting, or for detecting and distinguishing between or among colorectal cell proliferative disorders. The invention discloses genomic sequences the methylation patterns of which have utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.

Methods And Nucleic Acids For The Analysis Of Colorectal Cell Proliferative Disorders

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US Patent:
20070184438, Aug 9, 2007
Filed:
Jun 23, 2004
Appl. No.:
10/562377
Inventors:
Andrew Sledziewski - Shoreline WA, US
Jeff Thomas - Bellevue WA, US
Robert Day - Seattle WA, US
Lori Tonnes-Priddy - Everett WA, US
Karen Cardon - Renton WA, US
International Classification:
C12Q 1/68
C12M 3/00
C07H 21/04
US Classification:
435006000, 536024300, 435287200
Abstract:
Various aspects of the present invention provide novel diagnostic and prognostic methods for detecting, or for detecting and differentiating between or among colorectal cell proliferative disorders. Preferably, said colorectal cell proliferative disorders are selected from the group consisting of colorectal carcinoma, colon adenomas, and colon polyps. The inventive methods are based on analysis of differential CpG dinucleotide methylation of genomic DNA between or among normal and disease states. Additional embodiments provide nucleic acids and oligomers (including oligonucleotides and peptide nucleic acid (PNA)-oligomers), nucleic acid arrays and kits useful for practicing said methods, and in otherwise detecting, or detecting and differentiating between or among colorectal cell proliferative disorders.

Methods And Nucleic Acids For Analyses Of Colorectal Cell Proliferative Disorders

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US Patent:
20080064029, Mar 13, 2008
Filed:
Jun 23, 2004
Appl. No.:
10/562383
Inventors:
Fabian Model - Seattle WA, US
Andrew Sledziewski - Shoreline WA, US
Tamas Rujan - Berlin, DE
Jorn Lewin - Berlin, DE
Jurgen Distler - Berlin, DE
International Classification:
C12Q 1/68
C07H 21/00
US Classification:
435 6, 536 231
Abstract:
The invention provides methods, nucleic acids and kits for detecting, or for detecting and distinguishing between or among colorectal cell proliferative disorders. The invention discloses genomic sequences the methylation patterns of which have utility for the improved detection of and differentiation between said class of disorders, thereby enabling the improved diagnosis and treatment of patients.
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Andrew Z Sledziewski from Shoreline, WA, age ~72 Get Report