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Andrew S Khalil

from Cambridge, MA
Age ~38
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Also known as:
Andrew Z Khalil, Andrew Khalila
Related to:
Joyce Bryan, 87James Linwood Rice, 87
Connected to:
Adam N Khalil, 36Adil Khalil, 44Ahed M Khalil, 57Akram Khalil, 43Anthony G Khalil, 44Bashir I Khalil, 84Belita L Khalil, 76Bishoy M Khalil, 54Bryan M Khalil, 33Busaina L Khalil, 73

Andrew Khalil Phones & Addresses

  • Cambridge, MA
  • Madison, WI
  • Charleston, SC
  • Folly Beach, SC
  • 2302 University Ave APT 337, Madison, WI 53726

Work

Position: Clerical/White Collar

Resumes

Resumes

Andrew Khalil Photo 1

Postdoctoral Research Fellow

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Location:
375 Broadway, Cambridge, MA 02139
Industry:
Biotechnology
Work:
Wyss Institute For Biologically Inspired Engineering
Postdoctoral Research Fellow
Whitehead Institute
Postdoctoral Research Fellow
University of Wisconsin-Madison 2012 - Dec 2017
Doctoral Candidate
Stem Pharm Nov 2015 - Jun 2016
Graduate Student Intern
Education:
University of Wisconsin - Madison 2012 - 2017
Doctorates, Doctor of Philosophy, Biomedical Engineering, Bioengineering, Philosophy College of Charleston 2008 - 2011
Bachelors, Bachelor of Science, Molecular Biology, Biochemistry
Skills:
Gene Delivery
Biomaterials
Stem Cell Engineering
Molecular and Cellular Biology
Microscopy
Andrew Khalil Photo 2

Andrew Khalil

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Andrew Khalil

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Andrew Khalil

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Publications

Us Patents

Delivery Of Biologics Via Mineral Crystals For Regenerative Medicine Applications

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US Patent:
20230035942, Feb 2, 2023
Filed:
Jul 21, 2022
Appl. No.:
17/814128
Inventors:
- Madison WI, US
Gianluca Fontana - Madison WI, US
Andrew Khalil - Madison WI, US
Jae-Sung Lee - Madison WI, US
International Classification:
A61K 9/50
C12N 15/88
A61K 48/00
Abstract:
Disclosed are compositions having mineral crystals and biological molecules for the delivery of the biological materials and methods for preparing mineral crystals having a biologic material.

Mineral Coated Microparticles For Co-Delivery Of Anti-Inflammatory Molecules With Nucleic Acids To Improve Gene Delivery Outcomes

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US Patent:
20210353549, Nov 18, 2021
Filed:
Jul 19, 2021
Appl. No.:
17/379351
Inventors:
- Madison WI, US
Andrew Salim Khalil - Madison WI, US
Xiaohua Yu - Mansfield Center CT, US
International Classification:
A61K 9/50
A61K 38/16
Abstract:
Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral Layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins.

Structured Nanocoatings For The Stabilization Of Pluripotent Stem Cell Media Components

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US Patent:
20210145757, May 20, 2021
Filed:
Apr 5, 2019
Appl. No.:
17/045293
Inventors:
- Madison WI, US
Andrew Khalil - Madison WI, US
Angela Xie - Middleton WI, US
Hunter Johnson - Brooklyn WI, US
International Classification:
A61K 9/50
C12N 5/0735
C12N 5/074
Abstract:
Disclosed are compositions and methods for pluripotent stem cell culture. Compositions include mineral coated microparticles having a core and a mineral coating, wherein the mineral coating includes fibroblast growth factor. Also disclosed are methods for pluripotent stem cell culture methods using mineral coated microparticles including fibroblast growth factor.

Mineral Coated Microparticles For Co-Delivery Of Anti-Inflammatory Molecules With Nucleic Acids To Improve Gene Delivery Outcomes

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US Patent:
20200170958, Jun 4, 2020
Filed:
Jul 5, 2018
Appl. No.:
16/626973
Inventors:
- Madison WI, US
Andrew Salim Khalil - Madison WI, US
Xiaohua Yu - Mansfield Center CT, US
International Classification:
A61K 9/50
A61K 38/16
Abstract:
Disclosed are compositions and methods for the co-delivery of ribonucleic acids and interferon binding proteins. Compositions include mineral coated microparticles having a mineral layer, a ribonucleic acid, and an interferon binding protein. Ribonucleic acids and interferon binding proteins can be adsorbed to the mineral layer, can be incorporated into the mineral layer, and combinations thereof. Also disclosed are methods for co-delivery of ribonucleic acids and interferon binding proteins and methods for treating inflammatory diseases using mineral coated microparticles having a mineral layer to provide co-delivery of ribonucleic acids and interferon binding proteins.

Mineral Coated Microparticles For Gene Delivery In Chronic Wound Therapy

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US Patent:
20200138976, May 7, 2020
Filed:
Jul 5, 2018
Appl. No.:
16/626971
Inventors:
- Madison WI, US
Andrew Salim KHALIL - Madison WI, US
Xiaohua YU - Mansfield Center CT, US
International Classification:
A61K 48/00
A61K 9/50
Abstract:
Disclosed are formulations for providing a therapeutic bioactive polypeptide to injured tissue. Formulations include mineral coated microparticles wherein a polynucleotide is adsorbed to the mineral layer. Other formulations include a carrier including mineral coated microparticles wherein mineral coated microparticles include a polynucleotide. Also disclosed are methods for sustained delivery of a bioactive polypeptide and methods for treating chronic wounds using a formulation for providing sustained delivery of the bioactive peptide.

Inorganic Coatings For The Enhancement Of Chemical Transfection

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US Patent:
20160017368, Jan 21, 2016
Filed:
Sep 30, 2015
Appl. No.:
14/871327
Inventors:
- Madison WI, US
Andrew Salim Khalil - Madison WI, US
Xiaohua Yu - Mansfield CT, US
Krishanu Saha - Middleton WI, US
Benjamin Gabriel Steyer - Madison WI, US
International Classification:
C12N 15/85
Abstract:
Disclosed are methods for cell transfection and regulating cellular behavior. More particularly, the present disclosure relates to methods of non-viral cell transfection and regulating cellular behavior using mineral coatings that allow for the enhanced transfection of cells with reduced cytotoxicity. The mineral coatings bind biomaterials and provide a source of calcium and phosphate ions to enhance transfection. The present disclosure also provides a high throughput platform for screening non-viral transfection of cells. The methods of the present disclosure also provide an advantageous biomaterial delivery platform because the mineral coatings may be deposited on various medical device materials after being specifically developed using the high throughput screening platform.
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Andrew S Khalil from Cambridge, MA, age ~38 Get Report