Inventors:
Andrew Combs - Kennett Square PA, US
Eddy Yue - Landenberg PA, US
Michael Bower - Newark DE, US
Wenyu Zhu - Media PA, US
Matthew Crawley - Swarthmore PA, US
Richard Sparks - Boothwyn PA, US
James Pruitt - Landenberg PA, US
Amy Takvorian - Swedesboro NJ, US
International Classification:
C07D417/04
C07D275/02
A61K031/425
US Classification:
514340000, 514372000, 546271100, 548213000
Abstract:
The present invention provides compounds that can modulate the activity of a target protein, such as a phosphatase, that selectively binds phosphorylated peptides or proteins. The present compounds can be useful in treating diseases or disorders, including, for example, diabetes and obesity, that are connected directly or indirectly to the activity of the target protein.