Amit S Paranjape

20180296268, Oct 18, 2018

Apr 14, 2017

15/487466

- Wayland MA, US
Amit Paranjape - Acton MA, US
Kevin Schomacker - Maynard MA, US
Craig Langlois - Clinton MA, US
Herbert Otterson - Needham MA, US

A61B 18/20
B01D 46/00
A61N 5/06
A61M 1/00

Smoke evacuation system for removal of aerosolized chemical compounds and biological fine particles produced during laser treatment of tissue. The rapid smoke evacuation is achieved by coupling a low capacity vacuum pump to a vacuum valve and a vacuum reservoir to create very high flow rate for very short durations. The opening time of the valve could at least partially overlap the laser pulse duration.

20140368792, Dec 18, 2014

Jun 18, 2014

14/308678

- Waltham MA, US
David Muller - Boston MA, US
Amit Paranjape - Waltham MA, US

A61B 3/107
A61B 3/14
A61B 3/113
A61B 3/10

351206, 351212, 351209, 351246

A system for determining biomechanical properties of corneal tissue includes a light source configured to provide an incident light and a confocal microscopy system configured to scan the incident light across a plurality of cross-sections of corneal tissue. The incident light is reflected by the corneal tissue as scattered light. The system also includes a filter or attenuating device configured to block or attenuate the Rayleigh peak frequency of the scattered light, a spectrometer configured to receive the scattered light and process frequency characteristics of the received scattered light to determine a Brillouin frequency shift in response to the Rayleigh peak frequency being blocked or attenuated by the filter or attenuating device, and a processor configured to generate a three-dimensional profile of the corneal tissue according to the determined Brillouin frequency shift. The three-dimensional profile provides an indicator of one or more biomechanical properties of the corneal tissue.

20140368793, Dec 18, 2014

Jul 18, 2014

14/335372

- Waltham MA, US
David Muller - Boston MA, US
Amit Paranjape - Waltham MA, US

A61B 3/00
G01J 3/44
A61B 3/15
G02B 27/00
A61B 3/10
A61B 3/14

351206, 351221, 351246

A system for determining biomechanical properties of corneal tissue includes a light source configured to provide an incident light and a confocal microscopy system configured to scan the incident light across a plurality of cross-sections of corneal tissue. The incident light is reflected by the corneal tissue as scattered light. The system also includes a filter or attenuating device configured to block or attenuate the Rayleigh peak frequency of the scattered light, a spectrometer configured to receive the scattered light and process frequency characteristics of the received scattered light to determine a Brillouin frequency shift in response to the Rayleigh peak frequency being blocked or attenuated by the filter or attenuating device, and a processor configured to determine a three-dimensional profile of the corneal tissue according to the determined Brillouin frequency shift. The three-dimensional profile provides an indicator of one or more biomechanical properties of the corneal tissue.