Search

Alemseged A Truneh

from Salisbury, MA
Age ~73
Get Report
Also known as:
Alem Truneh, Alem Seged Truneh, T H
Related to:
Crystal Lynn Bray, 57T HKeddy Yemane, 67
Connected to:
Damion I Trunell, 52Nathan E Trunfio, 38Chi Trung, 54Huy S Trung, 34Kieu Trung, 81Kenneth R Trunk, 71Maria A Trunk, 58Mary C Trunk, 63Thomas E Trunk, 59Vivian K Trunk, 81

Alemseged Truneh Phones & Addresses

  • Salisbury, MA
  • Woburn, MA
  • 1008 Stoneham Dr, West Chester, PA 19382 (610) 640-4765
  • 93 Atkinson Ln, Sudbury, MA 01776 (978) 443-6278
  • Brighton, MA
  • King of Prussia, PA
  • Waltham, MA

Business Records

Name / Title
Company / Classification
Phones & Addresses
Alemseged Truneh
President
SYNAPTEX, INC
93 Atkinson Ln, Sudbury, MA 01776

Publications

Us Patents

Ligands Of Hvem For Treating Hematologic Malignancies

View page
US Patent:
8318166, Nov 27, 2012
Filed:
Jun 2, 2008
Appl. No.:
12/602539
Inventors:
Daniel Olive - Marseilles, FR
Alemseged Truneh - Sudbury MA, US
Christine Pasero - Marseilles, FR
International Classification:
A61K 39/395
US Classification:
4241411
Abstract:
The present invention relates to ligands of HVEM for the treatment of hematologic malignancies, in particular Chronic lymphocytic leukaemia, and for the treatment of autoimmune diseases.

Vaccine For Treatment And Prevention Of Herpes Simplex Virus Infection

View page
US Patent:
8541002, Sep 24, 2013
Filed:
Sep 13, 2004
Appl. No.:
10/571716
Inventors:
Alemseged Truneh - Sudbury MA, US
Daniel L. Levey - Boston MA, US
Xiaoyan Mo - Boxborough MA, US
Kenneth P. Leclair - Needham MA, US
Ramesh S. Kashi - Warren NJ, US
Chuanliang Liu - King of Prussia PA, US
Assignee:
Agenus Inc. - Lexington MA
International Classification:
A61K 39/385
A61K 38/02
A61K 39/245
US Classification:
42419611, 4242311, 4242781, 435 5
Abstract:
The present invention relates to methods and compositions for the prevention and treatment of herpes virus infections. The invention provides antigenic peptides, and pharmaceutical compositions comprising complexes of antigenic peptides and adjuvants that can activate an immune response against herpes viruses. The invention also provides methods of making the antigenic peptides and complexes of antigenic peptides and adjuvants. Methods of use of the pharmaceutical compositions are also provided.

Human Tumor Necrosis Factor Receptor-Like 2 (Tr2) Antibodies

View page
US Patent:
20020102258, Aug 1, 2002
Filed:
Dec 14, 2001
Appl. No.:
10/020787
Inventors:
Jeremy Harrop - Malvern PA, US
Stephen Holmes - Epsom, GB
Manjula Reddy - Phoenixville PA, US
Alemseged Truneh - West Chester PA, US
Assignee:
SmithKline Beecham Corporation
International Classification:
A61K039/395
US Classification:
424/143100
Abstract:
The present invention relates to antibodies to novel members of the Tumor Necrosis Factor (TNF) receptor family called TR2 receptor and their uses in pathological conditions. Hybridoma cell lines producing such mAbs, methods of in vivo imaging of pathological conditions, and methods of treating and diagnosing pathological conditions, caused by abnormal functioning, production or metabolism of TR2 receptors are also provided. In vitro assays for detecting the presence of TR2 and for evaluating the binding affinity of a test compound are also described.

Hexameric Fusion Proteins And Uses Therefor

View page
US Patent:
20020147326, Oct 10, 2002
Filed:
Apr 30, 2001
Appl. No.:
09/845899
Inventors:
Margery Chaikin - Wayne PA, US
Sally Lyn - West Chester PA, US
Raymond Sweet - Bala Cynwyd PA, US
Alemseged Truneh - West Chester PA, US
Assignee:
SmithKline Beecham Corporation
International Classification:
A61K039/395
C07H021/04
C12P021/04
C07K016/46
C12N005/06
US Classification:
536/023500, 435/326000, 435/320100, 424/178100, 530/389100, 435/069700
Abstract:
An hexameric fusion protein containing a dimeric binding protein provided with a tailpiece from an IgA antibody is described. This fusion protein is useful in therapeutics and vaccines, but is particularly well suited for applications for which the binding protein from which it is derived is unsatisfactory because of low binding affinity or for applications where multivalency is desired. These applications include diagnostics, binding assays and screening assays.

Anti-Rank Ligand Monoclonal Antibodies Useful In Treatment Of Rank Ligand Mediated Disorders

View page
US Patent:
20030211106, Nov 13, 2003
Filed:
Feb 19, 2003
Appl. No.:
10/344779
Inventors:
Mark Tornetta - Malvern PA, US
Raymond Sweet - Bala Cynwynd PA, US
Alemseged Truneh - King Of Prussia PA, US
Tervor Wattam - Harlow, GB
International Classification:
A61K039/395
C07H021/04
C12P021/02
C12N005/06
C07K016/40
G01N033/543
US Classification:
424/146100, 435/069100, 435/320100, 435/338000, 530/388260, 536/023530
Abstract:
Chimeric, humanized and other RANK-L MAbs, derived from high affinity neutralizing MAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.

Anti-Rank Ligand Monoclonal Antibodies Useful In Treatment Of Rank Ligand Mediated Disorders

View page
US Patent:
20040171117, Sep 2, 2004
Filed:
Dec 17, 2003
Appl. No.:
10/738809
Inventors:
Mark Tornetta - Malvern PA, US
Raymond Sweet - Bala Cynwyd PA, US
Alemseged Truneh - King of Prussia PA, US
Trevor Wattam - Harlow, GB
International Classification:
A61K039/395
C07H021/04
C07K016/28
C12N005/06
US Classification:
435/069100, 435/320100, 435/334000, 530/388220, 536/023530
Abstract:
Chimeric, humanized and other RANK-L MAbs, derived from high affinity neutralizing MAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.

Lipid Platinum Complexes And Methods Of Use Thereof

View page
US Patent:
20070160656, Jul 12, 2007
Filed:
May 3, 2004
Appl. No.:
10/555495
Inventors:
Krzysztof Dziewiszek - Acton MA, US
Alemseged Truneh - Sudbury MA, US
International Classification:
A61K 31/282
A61K 9/127
C07F 15/00
US Classification:
424450000, 554071000
Abstract:
This invention provides novel lipid platinum complexes, liposomally encapsulated lipid platinum complexes, pharmaceutical compositions comprising a lipid platinum complex, and methods for treating cancer using a lipid platinum complex. Kits comprising a unit dosage form of a compound or composition of the invention are also provided.

Pigr-1, A Member Of Immunoglobulin Gene Superfamily

View page
US Patent:
60201614, Feb 1, 2000
Filed:
Oct 22, 1997
Appl. No.:
8/955937
Inventors:
Shujian Wu - Levittown PA
Raymond W Sweet - Bala Cynwyd PA
Alemseged Truneh - West Chester PA
Mark Robert Hurle - Norristown PA
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C12N 1500
C12Q 168
C07H 2104
C07K 14705
US Classification:
435 691
Abstract:
PIGR-1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing PIGR-1 polypeptides and polynucleotides in the design of protocols for the treatment of rheumatoid arthritis (RA), multiple sclerosis (MS), psoriasis, systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD), among others and diagnostic assays for such conditions.
Control profile
Alemseged A Truneh from Salisbury, MA, age ~73 Get Report