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Albert S Bendelac

from Chicago, IL
Age ~67

Albert Bendelac Phones & Addresses

  • 1121 53Rd St, Chicago, IL 60615 (773) 643-0888
  • 528 Mercer St, Princeton, NJ 08540 (609) 924-5365
  • 8906 Old Georgetown Rd, Bethesda, MD 20814 (301) 564-1402

Publications

Us Patents

Adjuvants And Methods Of Use

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US Patent:
7794722, Sep 14, 2010
Filed:
Jun 29, 2007
Appl. No.:
11/771128
Inventors:
Luc Teyton - Del Mar CA, US
Albert Bendelac - Chicago IL, US
Paul B. Savage - Mapleton UT, US
Assignee:
The Scripps Research Institute - La Jolla CA
The University of Chicago - Chicago IL
Brigham Young University - Provo UT
International Classification:
A61K 39/00
A61K 39/38
A61K 45/00
A61K 47/00
A61K 31/70
A01N 43/04
US Classification:
4241841, 4242781, 514 25
Abstract:
Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune response are also disclosed. Further provided are vaccine preparations comprising NKT cell agonist compounds.

6″-Amino-6″-Deoxygalactosylceramides

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US Patent:
7989423, Aug 2, 2011
Filed:
Nov 24, 2009
Appl. No.:
12/625048
Inventors:
Paul B. Savage - Mapleton UT, US
Albert Bendelac - Chicago IL, US
Luc Teyton - Delmar CA, US
Assignee:
The Scripps Research Institute - La Jolla CA
Brigham Young University - Provo UT
The University of Chicago - Chicago IL
International Classification:
A61K 31/7028
A61P 31/04
US Classification:
514 25
Abstract:
This invention relates to galactosylceramide compounds.

Methods Of Activating Nkt Cells

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US Patent:
7998739, Aug 16, 2011
Filed:
Sep 2, 2005
Appl. No.:
11/218906
Inventors:
Albert Bendelac - Chicago IL, US
Dapeng Zhou - Chicago IL, US
Luc Teyton - Del Mar CA, US
Paul Savage - Mapleton UT, US
Assignee:
The Scipps Research Institute - La Jolla CA
Brigham Young University - Provo UT
The University of Chicago - Chicago IL
International Classification:
C12N 5/07
A61K 31/70
C07K 14/00
US Classification:
435375, 514 25, 514 54
Abstract:
Provided are methods of activating an NKT cell which include a step of contacting the NKT cell with a sufficient amount of isoglobotrihexosylceramide (iGb3) to induce secretion of a cytokine from the NKT cell, stimulate proliferation of the NKT cell or upregulate expression of a cell surface marker on the NKT cell. Methods of activating an NKT cell population in a subject are also provided.

Modified Α-Galactosyl Ceramides For Staining And Stimulating Natural Killer T Cells

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US Patent:
8227581, Jul 24, 2012
Filed:
Apr 9, 2007
Appl. No.:
12/296169
Inventors:
Paul B. Savage - Mapleton UT, US
Luc Teyton - Del Mar CA, US
Albert Bendelac - Chicago IL, US
Assignee:
The Scripps Research Institute - La Jolla CA
The University of Chicago - Chicago IL
Brigham Young University - Provo UT
International Classification:
A61K 39/00
A61K 39/7028
A61K 38/17
C07H 15/04
US Classification:
536 111, 536 179, 514 11, 514 24, 514 25, 4241841
Abstract:
Modified glycolipid compounds are provided. Also disclosed are methods for activating an NKT cell, methods of stimulating an immune response in a subject, and methods suitable for labeling NKT cells.

Method Of Stimulating Nkt With 6″-Amino-6″-Deoxygalactosylceramides

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US Patent:
8445272, May 21, 2013
Filed:
Aug 2, 2011
Appl. No.:
13/196631
Inventors:
Paul B. Savage - Mapleton UT, US
Albert Bendelac - Chicago IL, US
Luc Teyton - Delmar CA, US
Assignee:
The Scripps Research Institute - La Jolla CA
The University of Chicago - Chicago IL
Brigham Young University - Provo UT
International Classification:
C12N 5/06
C12N 5/00
A01N 25/00
A61K 31/739
US Classification:
435325, 435372, 514885, 514 25
Abstract:
This invention relates to galactosylceramide compounds.

6"-Amino-6"-Deoxygalactosylceramides

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US Patent:
20060264382, Nov 23, 2006
Filed:
Mar 20, 2003
Appl. No.:
10/550165
Inventors:
Paul Savage - Mapleton UT, US
Albert Bendelac - Chicago IL, US
Luc Teyton - Del Mar CA, US
Assignee:
BRIGHAM YOUNG UNIVERSITY - Provo UT
International Classification:
A61K 31/7008
US Classification:
514023000, 536053000
Abstract:
This invention relates to galactosylceramide compounds.

Bacterial Glycolipid Activation Of Cd1D-Restricted Nkt Cells

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US Patent:
20080279894, Nov 13, 2008
Filed:
Jan 26, 2006
Appl. No.:
11/814103
Inventors:
Paul B. Savage - Mapleton UT, US
Albert Bendelac - Chicago IL, US
Luc Teyton - Del Mar CA, US
Assignee:
BRIGHAM YOUNG UNIVERSITY - Provo UT
THE UNIVERSITY OF CHICAGO - Chicago IL
THE SCRIPPS RESEARCH INSTITUTE - La Jolla CA
International Classification:
A61K 39/02
C12N 5/06
A61K 39/00
US Classification:
4242341, 435375, 4241841
Abstract:
Disclosed are methods for activating an NKT cell, methods of stimulating an immune response in a subject, methods of improving vaccine efficacy, and methods of treating an infection. Also disclosed are methods of promoting tumor rejection, treating cancer, modulating autoimmunity and inhibiting allergen-induced hypersensitivity in subjects. The methods include contacting an NKT cell with a bacterial glycolipid complexed with a CD1 molecule to activate the NKT cell. The bacterial glycolipid may be derived from a member of the Class Alphaproteobacteria.

Adjuvants And Methods Of Use

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US Patent:
20110027323, Feb 3, 2011
Filed:
Aug 4, 2010
Appl. No.:
12/850428
Inventors:
Luc Teyton - Del Mar CA, US
Albert Bendelac - Chicago IL, US
Paul B. Savage - Mapleton UT, US
Assignee:
The Scripps Research Institute - La Jolla CA
The University of Chicago - Chicago IL
Brigham Young University - Provo UT
International Classification:
A61K 39/00
A61K 31/7028
C12N 5/071
C12N 5/0783
A61P 37/04
US Classification:
4242771, 514 23, 514 25, 435375, 4241841
Abstract:
Compositions comprising NKT cell agonist compounds and a physiologically acceptable vehicle are provided. Methods of stimulating an NKT cell and enhancing an immune response are also disclosed. Further provided are vaccine preparations comprising NKT cell agonist compounds.
Albert S Bendelac from Chicago, IL, age ~67 Get Report