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Alanna Schepartz Shrader

from Berkeley, CA
Age ~62

Alanna Shrader Phones & Addresses

  • Berkeley, CA
  • 3 Loomis Pl, New Haven, CT 06511 (203) 257-2623
  • 4 Borglum Rd, Wilton, CT 06897
  • New York, NY
  • Darien, CT
  • Rego Park, NY
  • Pasadena, CA
  • 3 Loomis Pl, New Haven, CT 06511

Publications

Us Patents

Protein Binding Miniature Proteins

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US Patent:
7495070, Feb 24, 2009
Filed:
Nov 4, 2004
Appl. No.:
10/982727
Inventors:
Alanna Schepartz Shrader - Wilton CT, US
Jason W. K. Chin - Cambridge, GB
Reena Zutshi - Tucson AZ, US
Stacey E. Rutledge - Cambridge, GB
Tanya L. Schneider - Harpswell ME, US
Heather M. Volkman - New Haven CT, US
Assignee:
Yale University - Hartsford CT
International Classification:
C07K 14/465
C07K 14/46
US Classification:
530324
Abstract:
The present invention provides a protein scaffold, such as an avian pancreatic polypeptide, that can be modified by substitution of two or more amino acid residues that are exposed on the alpha helix domain of the polypeptide when the polypeptide is in a tertiary form.

Β-Peptides

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US Patent:
8008262, Aug 30, 2011
Filed:
Apr 21, 2005
Appl. No.:
11/111218
Inventors:
Alanna Schepartz Shrader - Wilton CT, US
Scott A. Hart - San Diego CA, US
Joshua A. Kritzer - New Haven CT, US
Olen M. Stephens - New Haven CT, US
Assignee:
Yale University - New Haven CT
International Classification:
A61K 38/08
C08G 73/14
C12P 13/04
US Classification:
514 216, 525 5411, 435106, 436 90
Abstract:
β-peptide regions of polypeptides can serve as structural mimics of α-helices in wild type proteins. Because α-helices of one protein often bind to a target protein in a biological pathway, a polypeptide that contains a helical β-peptide region can be used to disrupt this type of protein-protein binding. As a result, polypeptides that contain a helical β-peptide region can be used to treat conditions involving this type of protein-protein binding, such as viral infections and cell proliferation.

Dna & Protein Binding Miniature Proteins

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US Patent:
20030166240, Sep 4, 2003
Filed:
Apr 24, 2001
Appl. No.:
09/840085
Inventors:
Alanna Shrader - Wilton CT, US
Jason Chin - San Diego CA, US
Reena Zutshi - Tucson AZ, US
Stacey Rutledge - New Haven CT, US
Joanne Kehlbeck Martin - Guilderland NY, US
Neal Zondlo - Newark DE, US
Assignee:
Yale University - New Haven CT
International Classification:
C12N009/64
C12Q001/70
C07H021/04
C12N007/00
C12P021/02
C12P021/06
C12N005/06
US Classification:
435/226000, 435/005000, 435/068100, 435/069100, 435/325000, 435/235100, 435/320100, 536/023200
Abstract:
The present invention provides a protein scaffold, such as an avian pancreatic polypeptide, that can be modified by substitution of two or more amino acid residues that are exposed on the alpha helix domain of the polypeptide when the polypeptide is in a tertiary form.

Protein Binding Miniature Proteins And Uses Thereof

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US Patent:
20050287643, Dec 29, 2005
Filed:
Dec 10, 2004
Appl. No.:
11/009101
Inventors:
Dasantila Golemi-Kotra - Thornhill, CA
Alanna Schepartz Shrader - Wilton CT, US
International Classification:
C07H021/04
C12P021/06
C07K014/575
A61K038/22
US Classification:
435069400, 435320100, 435349000, 514012000, 530399000, 536023500
Abstract:
In certain aspects, the present invention provides miniature proteins resulted from a protein scaffold such as an avian pancreatic polypeptide that can be modified by substitution of at least one amino acid residue. In other aspects, the present invention provides diagnostic and therapeutic uses of these miniature proteins.

Dna & Protein Binding Miniature Proteins

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US Patent:
20080108789, May 8, 2008
Filed:
Nov 2, 2007
Appl. No.:
11/982657
Inventors:
Alanna Shrader - Wilton CT, US
Jason Chin - San Diego CA, US
Reena Zutshi - New Haven CT, US
Stacey Rutledge - New Haven CT, US
Joanne Kehlbeck Martin - Guilderland NY, US
Neal Zondlo - Newark DE, US
Assignee:
Yale University - New Haven CT
International Classification:
C07K 14/00
C07K 7/00
US Classification:
530324000, 530300000, 530326000, 530327000, 530325000
Abstract:
The present invention provides a protein scaffold, such as an avian pancreatic polypeptide, that can be modified by substitution of two or more amino acid residues that are exposed on the alpha helix domain of the polypeptide when the polypeptide is in a tertiary form.

Protein Binding Miniature Proteins

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US Patent:
20110028686, Feb 3, 2011
Filed:
Oct 20, 2008
Appl. No.:
12/288401
Inventors:
Alanna Schepartz Shrader - Wilton CT, US
Jason W.K. Chin - San Diego CA, US
Reena Zutshi - New Haven CT, US
Stacey E. Rutledge - New Haven CT, US
Tanya L. Schneider - Harpswell ME, US
Heather M. Volkman - New Haven CT, US
Assignee:
Yale University - New Haven CT
International Classification:
C07K 2/00
C07K 14/765
C07K 16/00
C07K 1/107
US Classification:
530300, 530350, 530363, 5303911, 530402
Abstract:
The present invention provides a protein scaffold, such as an avian pancreatic polypeptide, that can be modified by substitution of two or more amino acid residues that are exposed on the alpha helix domain of the polypeptide when the polypeptide is in a tertiary form.

Novel Super-Resolution Imaging Compositions And Methods Using Same

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US Patent:
20160115180, Apr 28, 2016
Filed:
Oct 21, 2015
Appl. No.:
14/919216
Inventors:
- New Haven CT, US
Alanna Schepartz SHRADER - New Haven CT, US
Derek TOOMRE - New Haven CT, US
International Classification:
C07F 7/08
A61K 51/04
C07C 271/34
Abstract:
The invention provides compositions that may be used for imaging intracellular structures. The invention further provides methods of imaging intracellular structures. In certain embodiments, the compositions of the invention include trans-cyclooctene-containing ceramide lipids and tetrazine-containing rhodamine-related dyes.
Alanna Schepartz Shrader from Berkeley, CA, age ~62 Get Report