Inventors:
Xiaoling Zheng - Fremont CA
Yeung Siu Yu - Pleasanton CA
Adva Yani - Milpitas CA
Paing C. Huang - San Francisco CA
Assignee:
LifeScan, Inc. - Milpitas CA
International Classification:
C07C30900
Abstract:
8-(anilino)-1-naphthalenesulfonate (ANS) analogs and methods for their use in analyte detection assays are provided. The subject ANS analogs are characterized by having at least one non-hydrogen substituent on their phenyl moiety and producing a reaction product with 3-methyl-2-benzothiazolinone hydrazone hydrchloride (MBTH) or an analog thereof, e. g. MBTHSB, that exhibits reduced drift. In certain preferred embodiments, the subject ANS analogs are described by the formula: ##STR1## wherein: n is 1 to 5; and X is a substituent other than H. The subject ANS analogs find use in a variety of applications, particularly in analyte detection assays, such as glucose detection assays.