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Xiaoru X Chen

from San Diego, CA
Age ~60
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Also known as:
Xiao Ru Chen, Xiaoru Chen Wu, Xiangdong W Chen, Chen Wu Xiaoru, Dong Chen Xiangrong, U Chen
Phone and address:
13545 Golden Elm Ln, San Diego, CA 92129
(858) 216-6486
Related to:
Jenny WuXiangdong Wu, 56Yu J Chen, 62Jun Zhi Huang, 31John ChenGuifen ChenYan Nan Chen, 45Cheng Chen, 45Jing Wei ChenJames Chen, 42Shannon R Tucker, 38Jiang Z Wu, 56Fengzhi Chen, 49Huang Mang, 58Bonnie P Tucker, 69Yuxiu Chen, 62Yan Chen, 67Robert R Tucker, 69Zhengbing Chen, 55Zonyan Chen, 62Yi F Chen, 55
Connected to:
Aiyu Chen, 34Allen C Chen, 73Aluna F Chen, 58Anna D Chen, 67Annamaria E Chen, 38Annice B Chen, 31Anthony Chen, 60Ava H Chen, 43Baofeng Chen, 40Barbara K Chen, 46

Xiaoru Chen Phones & Addresses

  • 13545 Golden Elm Ln, San Diego, CA 92129 (858) 216-6486
  • 12675 Brickellia St, San Diego, CA 92129
  • 1413 E 15Th St, National City, CA 91950
  • 92 Berkeley, Irvine, CA 92612
  • Pullman, WA

Resumes

Resumes

Xiaoru Chen Photo 1

Associate Director R And D, Senior Scientist

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Location:
San Diego, CA
Industry:
Biotechnology
Work:
Diazyme Laboratories
Associate Director R and D, Senior Scientist
Diazyme Laboratories Nov 2000 - Mar 2012
Scientist and Senior Scientist
Dept of Chemical Engineering Uc Irvine Jan 2000 - Oct 2000
Postdoc Fellow
Dept of Biochemistry Washington State University Jan 1996 - Dec 1999
Postdoc Fellow
Dpet of Biomedical Engineering the Johns Hopkins University Mar 1995 - Dec 1995
Postdoc Fellow
Education:
Nankai University 1989 - 1992
Doctorates, Doctor of Philosophy, Organic Chemistry Central China Normal University 1986 - 1989
Master of Science, Masters, Organic Chemistry Hunan Normal University 1982 - 1986
Bachelors, Bachelor of Science, Chemistry
Skills:
Assay Development
Biotechnology
Molecular Biology
Cell Culture
Lifesciences
Protein Purification
In Vivo
Cell Biology
Pcr
Western Blotting
Drug Discovery
Gmp
Languages:
English
Mandarin
Xiaoru Chen Photo 2

Xiaoru Chen

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Location:
San Diego, CA
Industry:
Pharmaceuticals

Business Records

Name / Title
Company / Classification
Phones & Addresses
Xiaoru Chen
President
BEIJING ROYAL BUFFET INC
Eating Place
4 N Euclid Ave STE B, National City, CA 91950

Publications

Us Patents

Synthesis Of Functional Polymers And Block Copolymers On Silicon Oxide Surfaces By Nitroxide-Mediated Living Free Radical Polymerization In Vapor Phase

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US Patent:
6861103, Mar 1, 2005
Filed:
Feb 7, 2003
Appl. No.:
10/360443
Inventors:
Ying Chih Chang - Atherton CA, US
Jun Li - Irvine CA, US
Xiaoru Chen - San Diego CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C08F002/46
US Classification:
427522, 526220, 5263031, 526304, 5263171, 526346, 42725511, 42725514, 427487, 427593
Abstract:
Nitroxide mediated free radical polymerization of vaporized vinyl monomers, including acrylic acid (AAc), styrene (St), N-2-(hydroxypropyl)methacrylamide (HPMA) and N-isopropyl acrylamide (NIPAAm), on silicon wafers is demonstrated. FTIR, ellipsometry and contact angle goniometry were used to characterize the chemical structures, thickness and hydrophilicity of the films. The growth of film is linearly proportional to its reaction time, leading to the easy and exact control of polymer film thickness from nanometers to submicrons. The capability of polymerizing various monomers allows us to fabricate various functional polymer brushes. The reversible thermo-responsiveness of a 200 nm thick grafted poly(NIPAAm) film in aqueous solution is demonstrated with over 50% change in thickness at its lower critical solution temperature. A tri-block copolymer of poly(AAc)-b-polySt-b-poly(HPMA) is successfully synthesized, proving the renewability of TEMPO-mediated polymerization at vapor phase. Surface polymer composition and morphology is thus controlled at nanoscale by utilizing vapor phase surface-initiated controlled polymerization.

Hydrolase Enzyme Substrates And Uses Thereof

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US Patent:
20120190013, Jul 26, 2012
Filed:
Jan 17, 2012
Appl. No.:
13/352273
Inventors:
Xiaoru Chen - San Diego CA, US
International Classification:
C12Q 1/34
G01N 33/53
C12Q 1/44
C12Q 1/68
C07H 15/18
C07H 15/10
US Classification:
435 61, 536 41, 435 18, 435 19, 435 71
Abstract:
The present invention provides novel methods for determining the presence or amount of a hydrolytic enzyme in a sample, based on novel substrates for the enzymes, and also provides compositions and methods that provide highly sensitive assay methods for such hydrolytic enzymes.

Urease-Responsive Delivery Systems For Diagnostic And Therapeutic Applications

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US Patent:
61563463, Dec 5, 2000
Filed:
Jan 29, 1998
Appl. No.:
9/015502
Inventors:
Xiaoru Chen - Pullman WA
P. Jay Pasricha - Galveston TX
Kam W. Leong - Baltimore MD
Assignee:
Johns Hopkins University - Baltimore MD
International Classification:
A61K 914
A61K 950
US Classification:
424489
Abstract:
A delivery system that releases a diagnostic marker or therapeutic agent in a manner sensitive to the concentration of urease in a physiological compartment, particularly the gastrointestinal tract, and methods of use.

Methods And Compositions For Assaying Vitamin D

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US Patent:
20150212099, Jul 30, 2015
Filed:
Jan 30, 2014
Appl. No.:
14/169118
Inventors:
- San Diego CA, US
Fakhri Ben Habib SAIDA - San Diego CA, US
Xiaoru CHEN - San Diego CA, US
Chao DOU - San Diego CA, US
International Classification:
G01N 33/82
Abstract:
This invention generally relates to the field of vitamin D detection. In particular, the invention provides novel methods and kits for assaying a vitamin D moiety in a sample such as a biological fluid.

Hydrolase Enzyme Substrates And Uses Thereof

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US Patent:
20140370501, Dec 18, 2014
Filed:
Jun 19, 2014
Appl. No.:
14/309695
Inventors:
- San Diego CA, US
Xiaoru CHEN - San Diego CA, US
International Classification:
C12Q 1/34
C12Q 1/42
C12Q 1/44
C07H 15/203
C07H 15/10
US Classification:
435 611, 536 41, 435207, 435 18, 435 19, 435 21, 435 792, 435 61, 435 612
Abstract:
The present invention provides novel methods for determining the presence or amount of a hydrolytic enzyme in a sample, based on novel substrates for the enzymes, and also provides compositions and methods that provide highly sensitive assay methods for such hydrolytic enzymes.

Hydrolase Enzyme Substrates And Uses Thereof

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US Patent:
20140329241, Nov 6, 2014
Filed:
Jul 21, 2014
Appl. No.:
14/336816
Inventors:
- San Diego CA, US
Xiaoru Chen - San Diego CA, US
International Classification:
C12Q 1/34
C12Q 1/68
G01N 33/573
US Classification:
435 611, 435 18, 435 792, 435 61
Abstract:
The present invention provides novel methods for determining the presence or amount of a hydrolytic enzyme in a sample, based on novel substrates for the enzymes, and also provides compositions and methods that provide highly sensitive assay methods for such hydrolytic enzymes.

Methods And Compositions For Assaying Vitamin D

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US Patent:
20140162294, Jun 12, 2014
Filed:
Dec 6, 2012
Appl. No.:
13/707514
Inventors:
- San Diego CA, US
Xiaoru Chen - San Diego CA, US
Ruffy Baldemeca - San Diego CA, US
Assignee:
General Atomics - San Diego CA
International Classification:
G01N 33/82
US Classification:
435 792, 436501
Abstract:
The present invention provides methods for assaying a vitamin D moiety in a sample, using a water miscible organic solvent, a specific binding partner that specifically binds to said vitamin D moiety, the binding partner being different from a natural vitamin D binding protein for the vitamin D moiety, and a water soluble polymer that facilitates binding between the specific binding partner and the vitamin D moiety. Kits and reaction mixtures for assaying a vitamin D moiety in a sample are also provided.
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Xiaoru X Chen from San Diego, CA, age ~60 Get Report