US Patent:
20150079134, Mar 19, 2015
Inventors:
- New Brunswick NJ, US
Fei Chen - Denville NJ, US
Zhugong Liu - Boyds MD, US
Pankaj Mishra - Harrison NJ, US
Assignee:
Rutgers, The State University of New Jersey - New Brunswick NJ
International Classification:
A61K 35/62
A61K 39/00
Abstract:
The invention relates to a field of tissue repair and regeneration. More particularly, the invention relates to a composition for promoting cutaneous wound healing. In one embodiment, the composition is composed of one or more metazoan parasites or a mimic thereof sufficient to promote helminth-induced type-2 immune response. Preferably, the composition contains excretory/secretory antigen (NES) or an immune triggering portion thereof. The invention also relates to a method of accelerating wound healing in a subject in need of such treatment.