Inventors:
Ian S. Mitchell - Lafayette CO, US
James F. Blake - Longmont CO, US
Rui Xu - Longmont CO, US
Nicholas C. Kallan - Boulder CO, US
Dengming Xiao - Longmont CO, US
Keith Lee Spencer - Lyons CO, US
Josef R. Bencsik - Longmont CO, US
Eli M. Wallace - Lyons CO, US
Stephen T. Schlachter - Boulder CO, US
Anna L. Banka - Longmont CO, US
Jun Liang - Palo Alto CA, US
Brian Safina - Redwood City CA, US
Birong Zhang - Union City CA, US
Christine Chabot - San Mateo CA, US
Steven Do - San Jose CA, US
Assignee:
Array BioPharma Inc. - Boulder CO
Covenentech, Inc. - South San Francisco CA
International Classification:
C07D 239/70
A61K 31/496
A61P 35/00
Abstract:
The present invention provides compounds, including resolved enantiomers, resolved diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula I:Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.