Hongjun Jun Zhang

20050244836, Nov 3, 2005

Apr 28, 2004

10/834151

Xiangwen Meng - Skokie IL, US
Hongjun Zhang - Glenview IL, US

C12Q001/68
C12P019/34

435006000, 435091200

A novel multiplex polymerase chain reaction assay for detecting a bacteria (e.g. ) in a specimen uses multiple oligonucleotide primer pairs based on the sequences of multiple loci of the bacteria. In one application, up to five loci in the genomic DNA sequences of were amplified. Two fragments of were amplified from each locus, wherein a second fragment was an internal fragment of the first fragment.

20110287965, Nov 24, 2011

Nov 24, 2009

13/130846

Xiangwen Meng - Skokie IL, US
Hongjun Zhang - Glenview IL, US

TZAM DIAGNOSTICS LLC - Wilmette IL

C40B 30/04
C07H 21/04
C40B 30/00

506 9, 506 7, 536 2432, 536 2433

Methods for detecting strains of (e.g. toxigenic and non-toxigenic) in a specimen are disclosed. Oligonucleotide primer pairs based on the sequences of multiple loci of the bacteria are disclosed. In one application, up to five loci in the genomic DNA sequences of were amplified. Two fragments of were amplified from each locus, wherein a second fragment was an internal fragment of the first fragment.

20220361856, Nov 17, 2022

May 17, 2022

17/746392

- Vernon Hills IL, US
Hongjun ZHANG - Buffalo Grove IL, US

A61B 10/00

A fluid container including a container having a proximal end, a distal end, and an opening at the proximal end, a collecting chamber coupled to the proximal end of the container. The collecting chamber has a proximal end with an upper opening and a distal end with a lower opening, the upper opening having a diameter larger than a diameter of the lower opening. The fluid container further includes a cover with a base coupled to the proximal end of the collecting chamber and a stopper extending distally from a bottom of the base, the cover having an open position and a closed position. In the closed position, the cover seals the proximal end of the collecting chamber, and the stopper extends through the collecting chamber and in the open position, the cover exposes the upper opening, and the stopper is removed from the area proximate the lower opening.

20220235400, Jul 28, 2022

May 26, 2020

17/613737

- Vernon Hills IL, US
Hongjun ZHANG - Vernon Hills IL, US
Rajarao KAKUTURU - Vernon Hills IL, US
Zhaozhong CHONG - Vernon Hills IL, US

C12Q 1/689
C12Q 1/6806

The present disclosure provides methods and materials for detecting a level of in a sample.

20200095212, Mar 26, 2020

Feb 19, 2018

16/483957

- Rahway NJ, US
Dane Clausen - Rahway NJ, US
Liangqin Guo - Monroe Township NJ, US
Yongxin Han - Needham MA, US
Shuwen He - Fanwood NJ, US
Joseph Kozlowski - Princeton NJ, US
Derun Li - West Roxbury MA, US
Qinglin Pu - Needham MA, US
Wensheng Yu - Edison NJ, US
Hongjun Zhang - Boston MA, US

Merck Sharp & Dohme Corp. - Rahway NJ

C07D 271/08
C07D 413/12

Compounds of Formula I, or a pharmaceutically acceptable salt, solvate or hydrate thereof: (I). Also disclosed herein are uses of the compounds disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of the compositions in the potential treatment or prevention of an IDO-associated disease or disorder.

20150353498, Dec 10, 2015

Sep 26, 2013

14/432462

Xianhai HUANG - Rahway NJ, US
Anandan PALANI - Kenilworth NJ, US
Ashwin U. RAO - Kenilworth NJ, US
Hongjun ZHANG - Boston MA, US
Wei ZHOU - Rahway NJ, US
- Rahway NJ, US

Merck Sharp & Dohme Corp. - Rahway NJ

C07D 217/24
C07D 401/06
C07D 413/14
A61K 31/4725
C07D 413/04
A61K 31/472
A61K 31/496

The invention provides certain substituted isoquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters. The invention also provides pharmaceutical compositions comprising for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.