Inventors:
John R. Medich - East Hanover NJ, US
Hartmut Kupper - Mutterstadt, DE
John L. Perez - Doylestown PA, US
Jeffrey D. Kent - Deerfield IL, US
Eric H. Sasso - Mountain Lakes NJ, US
Oscar Segurado - Lake Bluff IL, US
George Spencer-Green - Mountain Lakes NJ, US
Theodore Pincus - Hastings-on-Hudson NY, US
International Classification:
A61K 39/395
A61J 1/00
A61K 31/4409
A61P 19/02
A61K 49/00
US Classification:
424 92, 4241581, 514354, 206438
Abstract:
The invention provides methods, uses and compositions for the treatment of rheumatoid arthritis. The invention describes methods and uses for treating rheumatoid arthritis wherein a TNFα inhibitor, such as a human TNFα antibody, or antigen-binding portion thereof. Also described are methods for determining the efficacy of a TNFα inhibitor for treatment of rheumatoid arthritis in a subject.