Chun Qi Lin

49719785, Nov 20, 1990

Aug 22, 1988

7/234525

Alex M. Nadzan - Libertyville IL
James F. Kerwin - Mundelein IL
Chun W. Lin - Wood Dale IL

C07D21522
A61K 3147

514312

A compound of the formula: ##STR1## wherein R. sub. 1 and R. sub. 2 are substituents; R. sub. 6 is hydrogen, loweralkyl, cycloalkyl, loweralkenyl, arylalkyl, (substituted aryl)alkyl, or (heterocyclic)alkyl; B is a bond, an alkylene group, an alkenylene group, an alkadienylene group or a heteroatom containing linking group; D is a substituted acyl group or tetrazolyl; Z is CO, C(S) or S(O). sub. 2 ; Ar is a heterocyclic group; and n is 1 to 3. Also disclosed are a composition and a method for antagonizing CCK, a composition and method for treating or preventing gastrointestinal, central nervous, appetite regulating and pain regulating systems, a composition and method for treating or preventing hyperinsulinemia, methods of making the compounds and intermediates useful in making the compounds.

51283468, Jul 7, 1992

Aug 23, 1990

7/571945

Alex M. Nadzan - Libertyville IL
James F. Kerwin - Mundelein IL
Chun W. Lin - Wood Dale IL

Abbott Laboratories - Abbott Park IL

H01N 4342
C07D20904

514307

A compound of the formula: ##STR1## wherein R. sub. 1 and R. sub. 2 are substituents; R. sub. 6 is hydrogen, loweralkyl, cycloalkyl, loweralkenyl, arylalkyl, (substituted aryl)alkyl, or (heterocyclic)alkyl; B is a bond, an alkylene group, an alkenylene group, an alkadienylene group or a heteroatom containing linking group; D is a substituted acyl group or tetrazolyl; Z is CO, C(S) or S(O). sub. 2 ; Ar is a heterocyclic group; and n is 1 to 3. Also disclosed are a composition and a method for antagonizing CCK, a composition and method for treating or preventing gastrointestinal, central nervous, appetite regulating and pain regulating systems, a composition and method for treating or preventing hyperinsulinemia, methods of making the compounds and intermediates useful in making the compounds.

52703029, Dec 14, 1993

Jun 17, 1991

7/713010

Kazumi Shiosaki - Libertyville IL
Alex M. Nadzan - Libertyville IL
Hana Kopecka - Vernon Hills IL
Youe-Kong Shue - Vernon Hills IL
Mark W. Holladay - Vernon Hills IL
Chun W. Lin - Wood Dale IL
Hugh N. Nellans - Mundelein IL

Abbott Laboratories - Abbott Park IL

A61K 3702
C07K 508
C07K 510

514 18

Selective and potent Type-A CCK receptor agonists of formula (I): X--Y--Z--Q (I) or a pharmaceutically acceptable salt thereof, wherein, X is selected from ##STR1## Y is selected from ##STR2## Z is ##STR3## and Q is ##STR4## or pharmaceutically-acceptable salts thereof, useful in the treatment of gastrointestinal disorders (including gallbladder disorders), central nervous system disorders, insulin-related disorders and pain, as well as in appetite regulation.

20090075097, Mar 19, 2009

Jul 25, 2008

12/179846

Cherie R. Kagan - Ossining NY, US
Chun Lin - Croton-On-Hudson NY, US

International Business Machines Corporation - Armonk NY

B32B 9/04

428450, 428704

The present invention provides a process for preparing a thin film having alternating monolayers of a metal-metal bonded complex monolayer and an organic monolayer by layer-by-layer growth. The process comprises the steps of: (1) applying onto a surface of a substrate a first linker compound to produce a primer layer; (2) applying onto said primer layer a layer of a metal-metal bonded complex to produce a metal-metal bonded complex monolayer on said primer layer; (3) applying onto said metal-metal bonded complex monolayer a second linker compound; and optionally (4) sequentially repeating steps (2) and (3) at least once to produce said layer-by-layer grown thin film having alternating monolayers of a metal-metal bonded complex monolayer and an organic monolayer.

20070148441, Jun 28, 2007

Mar 9, 2007

11/684506

Cherie Kagan - Ossining NY, US
Chun Lin - Croton-On-Hudson NY, US

INTERNATIONAL BUSINESS MACHINES CORPORATION - Armonk NY

B32B 9/04
B05D 3/10
B05D 7/00

428333000, 428447000, 428411100, 427301000, 427333000, 427407100, 977882000, 977883000

The present invention provides a process for preparing a thin film having alternating monolayers of a metal-metal bonded complex monolayer and an organic monolayer by layer-by-layer growth. The process comprises the steps of: (1) applying onto a surface of a substrate a first linker compound to produce a primer layer; (2) applying onto said primer layer a layer of a metal-metal bonded complex to produce a metal-metal bonded complex monolayer on said primer layer;(3) applying onto said metal-metal bonded complex monolayer a second linker compound; and optionally(4) sequentially repeating steps (2) and (3) at least once to produce said layer-by-layer grown thin film having alternating monolayers of a metal-metal bonded complex monolayer and an organic monolayer.